postsurgical pain Clinical Trials

11 recruitingLast updated: May 9, 2026

There are 11 actively recruiting postsurgical pain clinical trials across 10 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4. Top locations include Antwerp, Belgium, Arnhem, Netherlands, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


postsurgical pain Trials at a Glance

11 actively recruiting trials for postsurgical pain are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Antwerp, Arnhem, and Beijing. Lead sponsors running postsurgical pain studies include Chinese University of Hong Kong, Dalin Tzu Chi General Hospital, and Centre Hospitalier Universitaire, Amiens.

Browse postsurgical pain trials by phase

Treatments under study

About postsurgical pain Clinical Trials

Looking for clinical trials for postsurgical pain? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new postsurgical pain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about postsurgical pain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Not Applicable

Intertransverse Process Block to Improve Quality of Recovery and Pain Management in Adult Cardiac Surgical Patients

Chronic Postsurgical Pain
Chinese University of Hong Kong96 enrolled1 locationNCT06946290
Recruiting

Investigate and Predict Aortic & Thoracic Surgery Persistenet Postsurgical Pain

Persistent Postsurgical Pain
Queen Mary University of London60 enrolled1 locationNCT05369130
Recruiting
Not Applicable

Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery

Emergency surgeryPostoperative PainRisk Factors+3 more
Centre Hospitalier Universitaire, Amiens693 enrolled1 locationNCT06555107
Recruiting
Phase 4

Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty

Osteoarthritis, KneeTotal Knee ArthroplastyChronic Postsurgical Pain
Vanderbilt University Medical Center148 enrolled1 locationNCT06083480
Recruiting
Phase 3

Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty

postsurgical pain
KAZM Pharmaceuticals Inc.288 enrolled2 locationsNCT06202989
Recruiting
Phase 2

A Study on TLC590 for Managing Postsurgical Pain

Postsurgical Pain Management
TLC Biopharmaceuticals, Inc.120 enrolled2 locationsNCT06574269
Recruiting
Phase 4

Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes

EsketamineDexmedetomidinepostoperative analgesia+2 more
Peking University First Hospital312 enrolled1 locationNCT06087510
Recruiting
Phase 2Phase 3

Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section

postsurgical painCesarean SectionChronic post-surgical pain
Dalin Tzu Chi General Hospital120 enrolled1 locationNCT06344169
Recruiting
Phase 2

Sustained Release Lidocaine for the Treatment of Postoperative Pain

postsurgical painPostoperative Pain
University of British Columbia120 enrolled2 locationsNCT05193227
Recruiting

The Follow-up After Shorter Tapes Study. Effectiveness and Safety of Shorter Trans-obturator Tapes.

postsurgical painStress Urinary IncontinenceFollow-Up Studies
University Hospital, Akershus750 enrolled1 locationNCT06731985
Recruiting
Not Applicable

Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain

Knee OsteoarthritisChronic Knee PainPersistent Postsurgical Pain
Ziekenhuis Oost-Limburg400 enrolled15 locationsNCT05407610