Postoperative Pain Clinical Trials

147 recruiting

Postoperative Pain Trials at a Glance

206 actively recruiting trials for postoperative pain are listed on ClinicalTrialsFinder across 6 cities in 32 countries. The largest study group is Not Applicable with 120 trials, with the heaviest enrollment activity in Cairo, Istanbul, and Chongqing. Lead sponsors running postoperative pain studies include Bursa City Hospital, Cairo University, and General Hospital of Ningxia Medical University.

Browse postoperative pain trials by phase

Treatments under study

About Postoperative Pain Clinical Trials

Looking for clinical trials for Postoperative Pain? There are currently 147 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Postoperative Pain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Postoperative Pain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 206 trials

Recruiting
Not Applicable

Comparing ACB+IPACK and ACB+BiFeS Block Combinations for Analgesia in Total Knee Arthroplasty

Postoperative PainTotal Knee Arthroplasty
Hitit University78 enrolled1 locationNCT07561333
Recruiting

Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery

Breast CancerPostoperative PainInflammation
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital150 enrolled1 locationNCT07547774
Recruiting

Analgesic Consumption in the Early Postoperative Period: A Prospective Observational PACU Study

Pain ManagementPostoperative PainAnalgesic Consumption
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital254 enrolled1 locationNCT07547618
Recruiting

Can Ultrasound-Guided Fascial Plane Blocks Reduce Postoperative Pulmonary Complications After Major Abdominal Surgery?

Postoperative Pain ManagementAbdominal SurgeriesPostoperative Pulmonary Complications (PPCs)
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital500 enrolled1 locationNCT07394816
Recruiting
Not Applicable

Efficacy of Ultrasound-Guided Erector Spinae Block for Postoperative Pain Management in Nephrectomy

Postoperative PainNephrectomyErector Spinae Plane Block
Bangladesh Medical University66 enrolled1 locationNCT07560267
Recruiting
Not Applicable

Reducing Opioid Use for Chronic Pain Patients Following Surgery

Opioid UsePostoperative PainChronic Pain+1 more
University Health Network, Toronto210 enrolled1 locationNCT03675386
Recruiting
Not Applicable

Parasternal vs. Combined Parasternal-Serratus Block in Cardiac Surgery

Postoperative PainCardiac Surgery
BEDİA MİNE HANEDAN70 enrolled1 locationNCT07522229
Recruiting
Not Applicable

USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

Postoperative PainCholelithiasisAcute Cholecystitis
Hitit University70 enrolled1 locationNCT07552701
Recruiting
Not Applicable

PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery.

Postoperative PainSurgical Blood LossLumbar Spinal Fusion Surgery
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau62 enrolled2 locationsNCT07550114
Recruiting

Pain Education After Rotator Cuff Surgery

Postoperative Pain ManagementRotator Cuff TearsKinesiophobia (Fear of Movement)+2 more
Elif Dilara Durmaz45 enrolled1 locationNCT06886932
Recruiting
Phase 3

RADA16 for Adult Tonsillectomy

Postoperative Pain
Rutgers, The State University of New Jersey134 enrolled2 locationsNCT07060495
Recruiting
Not Applicable

SPSIP Block and Opioid Use After MICS

Postoperative Pain ManagementSerratus Posterior Superior Intercostal Plane BlockHeart Valvular Disease+1 more
Ankara City Hospital Bilkent50 enrolled1 locationNCT07259824
Recruiting
Not Applicable

Dexmedetomidine vs Tramadol for Anxiety, Pain, and Hemodynamics in Hemorrhoidectomy

Postoperative PainHemorrhoidsPerioperative Anxiety
Yuzuncu Yil University90 enrolled1 locationNCT06860100
Recruiting
Phase 2Phase 3

Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management

Open Colorectal SurgeryAppendectomyPostoperative Pain+5 more
Dr. Asma Abdus Salam263 enrolled1 locationNCT06996561
Recruiting
Not Applicable

EXORA vs ESP Blocks in Laparoscopic Cholecystectomy

Postoperative Pain
Fayoum University Hospital114 enrolled1 locationNCT07187310
Recruiting
Not Applicable

Retrolaminar Analgesia for LuMbar Surgery

Postoperative PainBack Pain Lower Back ChronicLumbar Surgery
Universidad de los Andes, Chile50 enrolled1 locationNCT07334288
Recruiting
Not Applicable

Management of Postoperative Pain Following Free Gingival Graft Harvesting Using Ora-Aid Versus Acrylic Palatal Stent

Postoperative PainGingival RecessionsMucogingival Defects
Cairo University20 enrolled1 locationNCT07523802
Recruiting

Patients' Perceptions of Postoperative Analgesic Monitoring in Elective General Surgery

Pain ManagementPostoperative Pain
Agri Ibrahim Cecen University300 enrolled1 locationNCT07389330
Recruiting
Phase 4

Efficacy of Preventive Ketamine on Postoperative Pain

Postoperative Pain
Ain Shams University90 enrolled1 locationNCT04908579
Recruiting
Phase 4

Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery

Postoperative Pain ManagementOphthalmic Surgery
Zhongshan Ophthalmic Center, Sun Yat-sen University204 enrolled3 locationsNCT07269106