Phase 3 Preterm Clinical Trials
21 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 21 trials
Recruiting
Phase 3
Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries
Preterm BirthStillbirthSmall for Gestational Age (SGA)+1 more
NICHD Global Network for Women's and Children's Health1,134 enrolled7 locationsNCT06723392
Recruiting
Phase 3
Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation
Preterm Premature Rupture of Membrane
Assistance Publique - Hôpitaux de Paris850 enrolled1 locationNCT03976063
Recruiting
Phase 3
Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction
Pregnancy PretermFetal Growth RetardationStillbirth and Fetal Death
Monash University336 enrolled12 locationsNCT05651347
Not Yet Recruiting
Phase 2Phase 3
Autologous cord blood-derived cell therapy for extremely preterm infants: An international, multicentre randomised controlled trial
preterm brain injury
Monash Health334 enrolled3 locationsACTRN12624000968572
Recruiting
Phase 3Phase 4
Positive End-Expiratory Pressure (PEEP) Levels during Resuscitation of Preterm Infants at Birth (The POLAR Trial).
Preterm Birth
Murdoch Children's Research Institute906 enrolled11 locationsACTRN12618001686291
Active
Phase 3
Preventing Lung Disease Using Surfactant + Steroid (The PLUSS Trial)
Extremely preterm birthRespiratory distress syndrome
The Melbourne Children's Trial Centre1,060 enrolled18 locationsACTRN12617000322336
Recruiting
Phase 3
Intravenous pentoxifylline as adjunct therapy to improve long-term disability in preterm infants
Late-onset sepsis (LOS)Preterm infantsNecrotising enterocolitis (NEC)+1 more
University of Sydney1,800 enrolled25 locationsACTRN12616000405415
Completed
Phase 3Phase 4
Effect of single versus multi-strain probiotic supplementation on the time to full enteral feeds in preterm neonates – a double blind randomised controlled trial
faecal short chain fatty acidsgut colonisationenteral nutrition in preterm neonates
Gayatri Jape172 enrolled1 locationACTRN12615000940572
Recruiting
Phase 3
Hypotension in Threatened Preterm Labour Treating with Initial Loading Dose of 30 mg versus 40 mg Nifedipine
hypotension in threatened preterm pregnant who treated with nifedipine
Khon Kaen Hospital90 enrolled1 locationACTRN12612000517875
Completed
Phase 3
MAGENTA - Magnesium Sulphate at 30 to 34 weeks' gestational age: Neuroprotection Trial
Complications of preterm infantCerebral PalsyNeuroprotection
University of Adelaide1,676 enrolled1 locationACTRN12611000491965
Completed
Phase 2Phase 3
The safety and efficacy of a locally available probiotic in premature infants.
all cause mortality and time to full feeds in preterm very low birthweight neonatesNecrotising Enterocolitis
Womens and Childrens Health Service120 enrolled1 locationACTRN12609000374268
Completed
Phase 3
Australasian Antenatal Study To Evaluate the Role Of Intramuscular Dexamethasone versus Betamethasone prior to preterm birth to increase survival free of childhood neurosensory disability – a randomised controlled trial
Long-term childhood neurosensory disability following antenatal corticosteroids given to women at risk of preterm birth at less than 34 weeks gestatation
Women’s and Children’s Hospital, SA1,499 enrolled1 locationACTRN12608000631303
Completed
Phase 3
Randomised trial of dopamine vs dobutamine for treatment of low systemic blood flow in very preterm infants
Low systemic blood flow in preterm infants
A/Prof Nick Evans45 enrolled1 locationACTRN12607000152426
Terminated
Phase 3
BOOST II: Benefits Of Oxygen Saturation Targeting Study
Preterm infants
NHMRC Clinical Trials Centre1,200 enrolled1 locationACTRN12605000055606
Completed
Phase 3
Optimising very preterm infant outcomes: an evidence based screening and surveillance method
Disability of very preterm infant
The University of Queensland202 enrolled1 locationACTRN12606000472572
Completed
Phase 3
The DINO Trial
Preterm Infants < or = 32 weeks
National Health and Medical Research Council640 enrolled1 locationACTRN12606000327583
Completed
Phase 3
Skin exposure during conventional phototherapy in preterm infants: A Randomised Controlled Trial
Preterm infants with physiological jaundice
The University of Queensland60 enrolled1 locationACTRN12606000474550
Completed
Phase 3
International neonatal immunotherapy study
Infants with sepsis. Infants being treated with antibiotics are eligible. Infants can be preterm or term.
The University of Sydney5,000 enrolled1 locationACTRN12606000273583
Completed
Phase 3
Australasian Collaborative Trial of Magnesium Sulphate for the Prevention of Mortality and Cerebral Palsy in Infants Born Very Preterm.
Infants born very preterm (<30 weeks)
Prof Caroline Crowther1,178 enrolled1 locationACTRN12606000252516
Completed
Phase 3
Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial
Women at risk of preterm birth, at less than 32 weeks gestation, who have already received a course of prenatal corticosteroids.
Professor Caroline Crowther980 enrolled1 locationACTRN12606000318583