Phase 2 Primary Mediastinal Large B-cell Lymphoma (PMBCL) Clinical Trials

6 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 16 of 6 trials

Recruiting
Phase 1Phase 2

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaChronic Lymphocytic Leukemia+10 more
Vironexis Biotherapeutics Inc.32 enrolled9 locationsNCT06533579
Recruiting
Phase 1Phase 2

Study of Safety and Efficacy of TC011 in the Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma Patients

Diffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)Relapsed Large B-cell Lymphoma+3 more
TICAROS Co., Ltd.98 enrolled1 locationNCT07473167
Recruiting
Phase 2

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Primary Mediastinal Large B Cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)Primary Mediastinal Large B-Cell Lymphoma Refractory+3 more
Jennifer Crombie, MD35 enrolled2 locationsNCT05934448
Recruiting
Phase 2

A Study of WZTL-002 CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Large B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)Diffuse Large B-Cell Lymphoma, Not Otherwise Specified+1 more
Malaghan Institute of Medical Research60 enrolled3 locationsNCT06486051
Recruiting
Phase 1Phase 2

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Diffuse Large B Cell LymphomaFollicular LymphomaMarginal Zone Lymphoma+5 more
Medical College of Wisconsin100 enrolled1 locationNCT04186520
Recruiting
Phase 1Phase 2

Study of Efficacy and Safety of CRC01 in Adult Large B-cell Lymphoma Patients

High-grade B-cell LymphomaDiffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+3 more
Curocell Inc.91 enrolled1 locationNCT04836507