Phase 2 Primary Mediastinal Large B Cell Lymphoma Clinical Trials
5 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–5 of 5 trials
Recruiting
Phase 2
Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma
B-cell Non Hodgkin LymphomaBurkitt LymphomaHigh Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements+6 more
University of Washington18 enrolled1 locationNCT07097363
Recruiting
Phase 2
Pembro Plus CAR T-cell Therapy in R/R in PMBCL
Primary Mediastinal Large B Cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)Primary Mediastinal Large B-Cell Lymphoma Refractory+3 more
Jennifer Crombie, MD35 enrolled2 locationsNCT05934448
Recruiting
Phase 2
Emapalumab Prevention of CAR-T Cell Associated Toxicities
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaFollicular Lymphoma+4 more
Marcela V. Maus, M.D.,Ph.D.28 enrolled2 locationsNCT06550141
Recruiting
Phase 1Phase 2
Phase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell Lymphoma
Diffuse Large B Cell LymphomaLarge B-cell LymphomaPrimary Mediastinal Large B Cell Lymphoma+2 more
Pell Bio-Med Technology Co., Ltd.49 enrolled5 locationsNCT05326243
Recruiting
Phase 2
Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy
Primary Mediastinal Large B Cell LymphomaDiffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedTransformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Academic and Community Cancer Research United120 enrolled6 locationsNCT06238648