Phase 1 PROC Clinical Trials
12 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–12 of 12 trials
Recruiting
Phase 1Phase 2
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
Hearing DisordersHearing DisorderHearing+7 more
University of Colorado, Denver344 enrolled1 locationNCT07304024
Recruiting
Phase 1
Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors
Ovarian CancerEndometrial CancerOvarian Cancer Metastatic+4 more
Whitehawk Therapeutics, Inc.226 enrolled12 locationsNCT07444814
Recruiting
Phase 1
A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.
Endometrial CancerPlatinum Resistant Ovarian CancerPROC
Whitehawk Therapeutics, Inc.265 enrolled12 locationsNCT07470853
Recruiting
Phase 1Phase 2
Parathyroid Allotransplant for Treatment of Hypoparathyroidism
HypoparathyroidismHypoparathyroidism Post-surgicalHypoparathyroidism Postprocedural
Peter Stock3 enrolled1 locationNCT06961071
Recruiting
Phase 1
Comparison Between Epidural Analgesia and Intrathecal Opioid Analgesia for Pain Management in Open Nephrectomy
PainSurgical Procedure, UnspecifiedRenal Cancer
University Hospital of Split40 enrolled1 locationNCT06595329
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
Advanced Solid TumorMetastatic Solid TumorSoft Tissue Sarcoma (STS)+3 more
GI Innovation, Inc.358 enrolled11 locationsNCT05824975
Recruiting
Phase 1Phase 2
Umbilical-Cord-Derived Mesenchymal Stem Cells Injection for Chronic Radiation Proctitis
Chronic Radiation Proctitis
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.24 enrolled1 locationNCT06438809
Completed
Phase 1
Pilot Study of Assistive Listening Devices in Treating Auditory Processing Deficits in Neurofibromatosis Type 1
auditory processing deficits in children with Neurofibromatosis Type 1
Murdoch Children's Research Institute10 enrolled1 locationACTRN12619000525189
Not Yet Recruiting
Phase 1
Thioguanine Suppositories For Proctitis
proctitis
Mater Hospital Brisbane10 enrolled1 locationACTRN12616000602426
Completed
Phase 1
A pilot randomised open-label taste-testing study to evaluate the acceptability of chocolate-based midazolam in children
Children needing a sedating premedication prior to general anaesthesia for a surgical procedure
Princess Margaret Hospital150 enrolled1 locationACTRN12615000225516
Recruiting
Phase 1
A randomised double blind placebo controlled trial to determine whether topical pre-treatment of injection sites can reduce the pain associated with needles
Pain reduction associated with needle insertion for venous puncture or dermatological procedures
QuikMed Holdings PTY LTD50 enrolled1 locationACTRN12612000205831
Not Yet Recruiting
Phase 1
A Randomised Controlled Trial of Minimal Occlusive Volume (MOV) technique compared to Cuff Pressure Monitoring (CPM) in Endotracheal and Tracheal Cuff Management
Aspiration of orophayngeal secretions during cuff monitoring procedures
Royal Melbourne Institute of Technology University186 enrolledACTRN12607000339459