Phase 2 Prostate Cancer Clinical Trials

54 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 54 trials

Recruiting
Phase 2Phase 3

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Prostate Cancer
Novartis Pharmaceuticals443 enrolled52 locationsNCT06780670
Recruiting
Phase 2

Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancer

Prostate CancerMetastatic Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute26 enrolled2 locationsNCT05751941
Recruiting
Phase 1Phase 2

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Ovarian CancerEndometrial CancerProstate Cancer+5 more
PMV Pharmaceuticals, Inc300 enrolled76 locationsNCT04585750
Recruiting
Phase 2

Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy

Prostate CancerProstate CarcinomaProstate Neoplasm+12 more
Shehzad Basaria, M.D.60 enrolled1 locationNCT06957691
Recruiting
Phase 2

SHR-1701 in Combination With Stereotactic Body Radiotherapy in mCRPC

Prostate CancermCRPC (Metastatic Castration-resistant Prostate Cancer)
Fudan University66 enrolled3 locationsNCT07451795
Recruiting
Phase 2

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

Prostate Cancer
Astellas Pharma Global Development, Inc.218 enrolled12 locationsNCT07005154
Recruiting
Phase 1Phase 2

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

Prostate CancerMetastatic Castration-resistant Prostate CancerUrogenital Neoplasms+3 more
Blue Earth Therapeutics Ltd82 enrolled19 locationsNCT05413850
Recruiting
Phase 2

A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

Prostate Cancer
Debiopharm International SA66 enrolled37 locationsNCT06395753
Recruiting
Phase 2

Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer

Prostate CancerRefractory Cancer
Wake Forest University Health Sciences50 enrolled2 locationsNCT04337580
Recruiting
Phase 1Phase 2

Phase Ib/IIa Dose Escalation and Expansion Study of [²¹²Pb]Pb-ADVC001 in Metastatic Prostate Cancer (TheraPb - Phase I/II Study).

Prostate CancerMetastatic Castration-resistant Prostate CancerMetastatic Hormone Sensitive Prostate Cancer
AdvanCell Pty Limited100 enrolled3 locationsNCT05720130
Recruiting
Phase 2

Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer

Prostate Cancer
University of California, San Diego150 enrolled1 locationNCT06990542
Recruiting
Phase 2

Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance

Prostate CancerProstate Adenocarcinoma
University of California, San Francisco60 enrolled1 locationNCT03933670
Recruiting
Phase 2

Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors

Breast CancerProstate CancerCancer-related Fatigue
University of Colorado, Denver134 enrolled2 locationsNCT07001241
Recruiting
Phase 2

ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

Prostate Cancer
NYU Langone Health392 enrolled1 locationNCT06397703
Recruiting
Phase 2

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Phase 2

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins50 enrolled1 locationNCT06059118
Recruiting
Phase 1Phase 2

A Multicenter, Open-label, Non-randomized Phase I/IIa Clinical Trial to Evaluate INR102 Injection in Patients With Prostate Cancer

Prostate Cancer
Yunhe Pharmaceutical (Tianjin) Co., Ltd55 enrolled2 locationsNCT06970119
Recruiting
Phase 1Phase 2

Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors

Breast CancerOvarian CancerProstate Cancer+3 more
Acerand Therapeutics (Shanghai) Limited298 enrolled14 locationsNCT06380660
Recruiting
Phase 2

Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)

Prostate Cancer
University of Texas Southwestern Medical Center68 enrolled1 locationNCT07313241
Recruiting
Phase 2

Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer

Prostate CancerProstate Cancer Metastatic
Martha Mims130 enrolled3 locationsNCT03833921