Prosthesis Clinical Trials

70 recruitingLast updated: May 21, 2026

There are 70 actively recruiting prosthesis clinical trials across 25 countries. Studies span Not Applicable, Phase 3, Phase 4. Top locations include Austin, Texas, United States, Lyon, France, Bordeaux, France. Updated daily from ClinicalTrials.gov.


Prosthesis Trials at a Glance

70 actively recruiting trials for prosthesis are listed on ClinicalTrialsFinder across 6 cities in 25 countries. The largest study group is Not Applicable with 31 trials, with the heaviest enrollment activity in Austin, Lyon, and Bordeaux. Lead sponsors running prosthesis studies include Istituto Ortopedico Rizzoli, Liberating Technologies, Inc., and University Hospital, Ghent.

Browse prosthesis trials by phase

About Prosthesis Clinical Trials

Looking for clinical trials for Prosthesis? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Prosthesis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Prosthesis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 70 trials

Recruiting
Not Applicable

Transdermal Compress IDE Study

Prosthesis and Implants
Balmoral Medical company100 enrolled9 locationsNCT06134167
Recruiting

RETRO-PROSPECTIVE POSTMARKET CLINICAL STUDY FOR FX SHOULDER SOLUTIONS SHOULDER SYSTEMS

Glenohumeral OsteoarthritisAvascular Necrosis of the Head of HumerusInflammatory Arthritis+4 more
FX Solutions1,004 enrolled22 locationsNCT07558590
Recruiting
Not Applicable

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting

Corneal Melting in Boston Keratoprosthesis Type I
Centre hospitalier de l'Université de Montréal (CHUM)40 enrolled1 locationNCT03041883
Recruiting

Evaluation of the Clinical Outcomes of the Total Knee ps Prosthesis Implanted With the Use of Inertial Sensors

Prosthesis Durability
Istituto Ortopedico Rizzoli40 enrolled1 locationNCT06321042
Recruiting
Not Applicable

Clinical Performance of 3D-Printed Resin and Zirconia Implant Restorations

Prosthesis User
Menoufia University60 enrolled1 locationNCT07522671
Recruiting
Not Applicable

Comparing the Attentional Demands and Functional Outcomes in People With Transradial Amputation

AmputationProsthesis Use
Virginia Commonwealth University32 enrolled2 locationsNCT07075042
Recruiting
Not Applicable

Efficacy of Early Multimodal Physiotherapy in Patients With Reverse Shoulder Prosthesis

Shoulder FracturesProsthesis User
University of Malaga40 enrolled1 locationNCT06357143
Recruiting
Not Applicable

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Aortic Valve StenosisAortic Valve RegurgitationProsthesis Failure
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval310 enrolled7 locationsNCT05459233
Recruiting

A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System

OsteoarthritisPost-traumatic ArthritisTotal Ankle Replacement+1 more
Stryker Trauma and Extremities200 enrolled4 locationsNCT07118501
Recruiting
Not Applicable

Influence of Zirconia Abutments on Peri-Implant Tissues in Single-Tooth Restorations

Peri-implant healthImplant ComplicationProsthesis and Implants
University of Campinas, Brazil71 enrolled1 locationNCT07456163
Recruiting

Long Term Follow-up of Patients With Prosthetic Joint Infection of the Hip Treated at University Hospitals Leuven

Prosthetic joint infectionHip Prosthesis Infection
Universitaire Ziekenhuizen KU Leuven50 enrolled1 locationNCT05000723
Recruiting
Not Applicable

Studies Into Touch in Healthy Humans to Provide Sensory Feedback in Prostheses

AgingAmputationProsthesis User+2 more
Institut National de la Santé Et de la Recherche Médicale, France210 enrolled2 locationsNCT05548322
Recruiting
Not Applicable

Effect of Bilateral Rhomboid Intercostal Block on Postoperative Pain After Breast Implant Surgery

Postoperative PainBreast AugmentationBreast Prosthesis; Pain
Aydin Adnan Menderes University40 enrolled1 locationNCT07448246
Recruiting
Not Applicable

Clinical and Psychological Adjustment of Patients With LLA: a Multidisciplinary Rehabilitative Intervention Project

Lower limb amputationProsthesis User
Istituti Clinici Scientifici Maugeri SpA70 enrolled1 locationNCT06471855
Recruiting

Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)

Bone LossArthroplasty ComplicationsHip Prosthesis Infection
Istituto Ortopedico Rizzoli15 enrolled1 locationNCT06527664
Recruiting
Not Applicable

Artificial Intelligence Versus Conventional Digital Design for Fixed Dental Prosthesis

Accuracy of Artificial Intelligence in Fixed Dental Prosthesis Design
October University for Modern Sciences and Arts1,000 enrolled1 locationNCT07432165
Recruiting
Not Applicable

Clinical and Functional Assessment of Patients With Transfemoral Amputation Treated With Osteointegrated Implant

Amputation; Traumatic, Leg, LowerProsthesisLower Limb Amputation Knee
Istituto Ortopedico Rizzoli15 enrolled1 locationNCT06737770
Recruiting

Gender Disparities in Voice Outcomes After Tracheoesophageal Puncture in Total Laryngectomy Patients (UC Davis)

Total LaryngectomyLaryngectomy; StatusSpeech Disorders+2 more
University of California, Davis12 enrolled1 locationNCT05489965
Recruiting
Not Applicable

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

AmputationLower Limb Amputation Above Knee (Injury)Limb; Absence, Congenital, Lower+3 more
Hanger Institute for Clinical Research and Education, LLC100 enrolled1 locationNCT06937242
Recruiting
Not Applicable

Evaluation of Penile Prosthesis Pump Manipulation

Penile Prosthesis
Hospices Civils de Lyon60 enrolled1 locationNCT06376513