Phase 1 Psych Clinical Trials
21 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 21 trials
Recruiting
Phase 1
HNC: Human Neural Circuits Electrophysiology During Cognition
Psychiatric Disorder
Stanford University120 enrolled1 locationNCT05962424
Recruiting
Phase 1Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Clinical High Risk for Psychosis (CHR)
Monument Therapeutics Limited150 enrolled15 locationsNCT07226895
Recruiting
Phase 1Phase 2
Ocrelizumab for Psychosis by Autoimmunity
SchizophreniaSchizo-Affective Type of Psychosis
The Methodist Hospital Research Institute40 enrolled1 locationNCT03971487
Recruiting
Phase 1
The ENHANCE Study: taVNS and Psilocybin
HealthyVagus Nerve StimulationPsychedelic Experiences
University of Wisconsin, Madison108 enrolled1 locationNCT05866471
Recruiting
Phase 1
Writing About Experiences and Health in Older Adults II
Social Psychology
University of California, Los Angeles200 enrolled1 locationNCT05524597
Recruiting
Phase 1
Safety for Home Administration of Microdose Psilocybin Use
Psychedelic Experiences
Johns Hopkins University20 enrolled1 locationNCT06450210
Recruiting
Phase 1
Investigation of Psychedelic Effects in Psychoactive Substances
Psychedelic Effects in Healthy Volunteers
Johns Hopkins University50 enrolled1 locationNCT06772753
Recruiting
Phase 1
A Phase 1 MAD Study to Evaluate the Safety and Tolerability of LY03020
SchizophreniaAlzheimer's Disease Psychosis
Luye Pharma Group Ltd.40 enrolled1 locationNCT07230652
Recruiting
Phase 1
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: a Dimensional Approach
Neuropsychiatric Syndromes
The University of Texas Health Science Center, Houston200 enrolled1 locationNCT03705715
Recruiting
Phase 1
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
StressStress (Psychology)Stress, Psychologic+4 more
Center for Advanced Facial Plastic Surgery20 enrolled1 locationNCT06778421
Recruiting
Phase 1
Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis
PsychosisNegative Symptoms With Primary Psychotic Disorder
Bjorn H. Ebdrup46 enrolled1 locationNCT04789915
Recruiting
Phase 1
A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418
Parkinson Disease Psychosis
1ST Biotherapeutics, Inc.64 enrolled1 locationNCT05995782
Recruiting
Phase 1Phase 2
Psychedelic-assisted Group Program for First Responders
PsilocybinPsychotherapy, Group
Empower Research Inc32 enrolled1 locationNCT06471959
Recruiting
Phase 1
Biological and Behavioral Outcomes of Community Nature Walks
Stress, PsychologicalStress ReactionTelomere Shortening
Charlotte Tate200 enrolled1 locationNCT06056375
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine oral suspension against the innovator 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine oral tablet conducted under fasting conditions in healthy male and female volunteers.
3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine is indicated for treatment-resistant schizophrenic patients and in schizophrenia patients who have severe, untreatable neurological adverse reactions to other antipsychotic agents, including atypical antipsychotics.
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12621001490864
Completed
Phase 1
A study investigating safety, dosing and effectiveness of medicinal cannabis for symptom relief for patients with advanced cancer
Psychological effectsPainCancer+3 more
The University Of Queensland15 enrolled2 locationsACTRN12618001205224
Withdrawn
Phase 1
Repeatability and diurnal variation of eye responses measured with Neuro-Ophthalmic Device (NODe)
epilepsy or any type of seizureMild traumatic brain injury (mTBI) or concussionmedically diagnosed psychiatric disorder
Percy Lazon de la Jara20 enrolled1 locationACTRN12615000371594
Completed
Phase 1
The effects of a resistance training program (Cross-Fit Teens) on physiological and psychological health in adolescents: A randomized controlled trial.
Psychological healthBody CompositionPhysical Fitness
The University of Newcastle60 enrolled1 locationACTRN12613001310752
Not Yet Recruiting
Phase 1
Minimising Injury in Aged Care
Work-related physical and/or psychological injury in aged care workers
Aged Care Association of Australia (SA)500 enrolled1 locationACTRN12610000521022
Not Yet Recruiting
Phase 1
A comparison of intensive individualised behavioural support and traditional medical treatment for the behavioural and psychological symptoms of dementia (BPSD).
The behavioural and psychological symptoms of dementia (BPSD)
Dr Kuruvilla George, Consultant Psychiatrist and Director, Eastern Health's Aged Persons Mental Health Service90 enrolledACTRN12607000344493