Phase 1 Psych Clinical Trials
23 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 23 trials
Recruiting
Phase 1Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Clinical High Risk for Psychosis (CHR)
Monument Therapeutics Limited150 enrolled15 locationsNCT07226895
Recruiting
Phase 1
Yoga for Black and Brown Women Who Have Experienced Abuse From an Intimate Partner
Psychological Well-beingIntimate Partner Violence (IPV)Psychological Trauma, Historical
The University of Akron40 enrolled1 locationNCT07546266
Recruiting
Phase 1
HNC: Human Neural Circuits Electrophysiology During Cognition
Psychiatric Disorder
Stanford University120 enrolled1 locationNCT05962424
Recruiting
Phase 1Phase 2
Ocrelizumab for Psychosis by Autoimmunity
SchizophreniaSchizo-Affective Type of Psychosis
The Methodist Hospital Research Institute40 enrolled1 locationNCT03971487
Recruiting
Phase 1
The ENHANCE Study: taVNS and Psilocybin
HealthyVagus Nerve StimulationPsychedelic Experiences
University of Wisconsin, Madison108 enrolled1 locationNCT05866471
Recruiting
Phase 1
Writing About Experiences and Health in Older Adults II
Social Psychology
University of California, Los Angeles200 enrolled1 locationNCT05524597
Recruiting
Phase 1
Investigation of Psychedelic Effects in Psychoactive Substances
Psychedelic Effects in Healthy Volunteers
Johns Hopkins University50 enrolled1 locationNCT06772753
Recruiting
Phase 1
Safety for Home Administration of Microdose Psilocybin Use
Psychedelic Experiences
Johns Hopkins University20 enrolled1 locationNCT06450210
Recruiting
Phase 1
A Robot-assisted Tailored Activity Programme for People With Dementia and Their Caregivers
DementiaPhysical ActivityCaregiver+1 more
The Hong Kong Polytechnic University60 enrolled1 locationNCT07239869
Recruiting
Phase 1
A Phase 1 MAD Study to Evaluate the Safety and Tolerability of LY03020
SchizophreniaAlzheimer's Disease Psychosis
Luye Pharma Group Ltd.40 enrolled1 locationNCT07230652
Recruiting
Phase 1
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: a Dimensional Approach
Neuropsychiatric Syndromes
The University of Texas Health Science Center, Houston200 enrolled1 locationNCT03705715
Recruiting
Phase 1
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
StressStress (Psychology)Stress, Psychologic+4 more
Center for Advanced Facial Plastic Surgery20 enrolled1 locationNCT06778421
Recruiting
Phase 1
Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis
PsychosisNegative Symptoms With Primary Psychotic Disorder
Bjorn H. Ebdrup46 enrolled1 locationNCT04789915
Recruiting
Phase 1
A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418
Amyotrophic Lateral Sclerosis(ALS)Parkinson Disease Psychosis
1ST Biotherapeutics, Inc.64 enrolled1 locationNCT05995782
Recruiting
Phase 1Phase 2
Psychedelic-assisted Group Program for First Responders
PsilocybinPsychotherapy, Group
Empower Research Inc32 enrolled1 locationNCT06471959
Recruiting
Phase 1
Biological and Behavioral Outcomes of Community Nature Walks
Stress, PsychologicalStress ReactionTelomere Shortening
Charlotte Tate200 enrolled1 locationNCT06056375
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine oral suspension against the innovator 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine oral tablet conducted under fasting conditions in healthy male and female volunteers.
3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine is indicated for treatment-resistant schizophrenic patients and in schizophrenia patients who have severe, untreatable neurological adverse reactions to other antipsychotic agents, including atypical antipsychotics.
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12621001490864
Completed
Phase 1
A study investigating safety, dosing and effectiveness of medicinal cannabis for symptom relief for patients with advanced cancer
Psychological effectsPainCancer+3 more
The University Of Queensland15 enrolled2 locationsACTRN12618001205224
Withdrawn
Phase 1
Repeatability and diurnal variation of eye responses measured with Neuro-Ophthalmic Device (NODe)
epilepsy or any type of seizureMild traumatic brain injury (mTBI) or concussionmedically diagnosed psychiatric disorder
Percy Lazon de la Jara20 enrolled1 locationACTRN12615000371594
Completed
Phase 1
The effects of a resistance training program (Cross-Fit Teens) on physiological and psychological health in adolescents: A randomized controlled trial.
Psychological healthBody CompositionPhysical Fitness
The University of Newcastle60 enrolled1 locationACTRN12613001310752