Phase 4 Psych Clinical Trials
23 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 23 trials
Recruiting
Phase 4
Examining the Effects of Estradiol on Neural and Molecular Response to Reward
DepressionAnhedoniaPsychosis
University of North Carolina, Chapel Hill103 enrolled1 locationNCT05282277
Recruiting
Phase 4
"Extended" (Alternate Day) Antipsychotic Dosing
Drug TherapySchizophrenia and Related DisordersAntipsychotic Agents+1 more
Centre for Addiction and Mental Health120 enrolled1 locationNCT04478838
Recruiting
Phase 4
Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis
Cannabis UsePsychosis
Nova Scotia Health Authority24 enrolled2 locationsNCT07001878
Recruiting
Phase 4
Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease
Genital Diseases, MaleSexual Dysfunctions, PsychologicalPeyronie Disease
University of Miami22 enrolled2 locationsNCT05777031
Recruiting
Phase 4
Biomarkers in Clozapine-responding Schizophrenia
SchizophreniaPsychosis
Jimmi Nielsen200 enrolled1 locationNCT05316883
Recruiting
Phase 4
Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial
Tobacco Use DisorderPsychiatric DisorderNicotine Dependence
Centre for Addiction and Mental Health40 enrolled1 locationNCT06534047
Recruiting
Phase 4
Clozapine-related Immunodeficiency in Parkinsons Disease
ImmunodeficiencyPsychosisParkinson's Disease (PD)+1 more
Centre Hospitalier Universitaire, Amiens24 enrolled1 locationNCT06634641
Recruiting
Phase 4
Comparing Antipsychotic Medications in LBD Over Time
Dementia With Lewy BodiesParkinson's Disease Psychosis
The University of Texas Health Science Center at San Antonio94 enrolled2 locationsNCT05590637
Recruiting
Phase 4
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
Parkinson's Disease Psychosis
VA Office of Research and Development358 enrolled24 locationsNCT04373317
Recruiting
Phase 4
Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases
Parkinson DiseaseNeurodegenerative DiseasesParkinson Disease Psychosis
Vanderbilt University Medical Center75 enrolled1 locationNCT05357612
Recruiting
Phase 4
Evaluating the Effect of the STEP@STAH Semaglutide Protocol on the Physical Health Measures of Atypical Antipsychotic-Treated Patients
Obesity and Obesity-related Medical ConditionsPsychiatric Disorders
St Andrew's Healthcare20 enrolled1 locationNCT06754163
Recruiting
Phase 4
Psychopharmacological Treatment of Emotional Distress
Psychological DistressSuicide Crisis Syndrome
Icahn School of Medicine at Mount Sinai80 enrolled1 locationNCT06133114
Recruiting
Phase 4
Study investigating whether the drug semaglutide could be a safe and effective way of reducing metabolic problems, such as a high Body Mass Index (BMI) and high blood sugar levels, in people with psychosis.
Metabolic riskPsychosis
South Eastern Sydney Local Health District100 enrolled1 locationACTRN12621001434886
Terminated
Phase 4
What is the difference in the safety of Ketamine versus Propofol when used to sedate Acute Psychiatric/ Psychotic Patients who require Aeromedical Retrieval?
Personality DisorderAcute PsychosisDepression+3 more
CareFlight Limited400 enrolled1 locationACTRN12616001134415
Active
Phase 3Phase 4
Investigation of the Effects of Longvida Curcumin on Cognitive Function, Mood and Biomarkers of Health.
Brain function (fMRI)Psychological wellbeing (mood, stress fatigue, sleep)Inflammation+2 more
Swinburne University of Technology, Centre for Human Psychopharmacology80 enrolled1 locationACTRN12616000484448
Completed
Phase 4
The Efficacy of Sodium Benzoate as an Adjunctive Treatment in Early Psychosis
Early psychosis (including schizophrenia, schizophreniform psychosis, delusional disorder, bipolar disorder, psychosis not otherwise specified)
The University of Queensland100 enrolled9 locationsACTRN12615000187549
Completed
Phase 4
Effects of inhaled methoxyflurane (Penthrox) on psychomotor function in humans: a randomized placebo trial
Psychomotor function in humans who inhale methoxyflurane (Penthrox) as a mode of analgesia
Department of Gastroenterology and Hepatology, Royal Adelaide Hospital60 enrolled1 locationACTRN12613000666729
Completed
Phase 4
An open randomised clinical trial involving Haloperidol, Olanzapine, Quetiapine, Risperidone, and Ziprasidone in first episode never-treated psychosis
Antipsychotic discontinuation in first episode psychosis
Lilly150 enrolled1 locationACTRN12610000954022
Not Yet Recruiting
Phase 4
How does local anesthetic airway topicalisation, for awake fiberbreoptic intubation (AFOI), affect patient reaction time?
psychometric effect of lignocaine
Fremantle Hospital12 enrolled1 locationACTRN12610000459022
Terminated
Phase 4
A comparison study of quetiapine medication and psychological therapy versus placebo tablets and psychological therapy in patients who are deemed at risk of developing a psychotic disorder.
Prodromal Psychosis
Orygen Youth Health Research Centre163 enrolled2 locationsACTRN12610000244000