Phase 1 RAF Gene Mutation Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1Phase 2

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Non-small Cell Lung CancerMetastatic Lung CancerMetastatic Lung Non-Small Cell Carcinoma+18 more

Institut de Recherches Internationales Servier554 enrolled11 locationsNCT05786924

Recruiting

Phase 1

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

OncologyMEK MutationRAF Gene Mutation

Nested Therapeutics, Inc230 enrolled23 locationsNCT06326411

Recruiting

Phase 1

Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

Metastatic MelanomaBRAF Gene Mutation

Rina Plattner30 enrolled4 locationsNCT04903119