Phase 1 Reconstruction Clinical Trials
6 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–6 of 6 trials
Recruiting
Phase 1
Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon
Breast ReconstructionGenetic PredispositionPerfusion; Complications+1 more
Duke University25 enrolled1 locationNCT07264790
Recruiting
Phase 1Phase 2
Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction
Anterior Cruciate Ligament Reconstruction RehabilitationQuadriceps Muscle Function
Arcadia University42 enrolled1 locationNCT07128602
Not Yet Recruiting
Phase 1
Safety and feasibility of Poly Aryl Ether Ketone (PAEK) Implant for Contour Restoration in Jaw Reconstruction. A Pilot Trial
Facial asymmetryJaw reconstruction
Chris O'Brien Lifehouse12 enrolled1 locationACTRN12623001092684
Not Yet Recruiting
Phase 1
Safety and Efficacy of IntraOsseous Ropivacaine in Lower Extremity (SORE) Study
Anterior cruciate ligament reconstruction
Simon Young15 enrolled1 locationACTRN12619000700134
Completed
Phase 1
A randomised, double-blind, comparator study to assess the safety & tolerability of a single injection into the knee joint of MSB-CAR001 when combined with Hyaluronan compared to Hyaluronan alone in patients who have recently undergone an Anterior Cruciate Ligament Reconstruction.
Anterior Cruciate Ligament (ACL) reconstruction following an initial, unilateral acute ACL injury.Osteoarthritis post ACL repair
Mesoblast Ltd24 enrolled1 locationACTRN12609001018202
Recruiting
Phase 1
An evaluation of knee stability and functions following ACL reconstruction (semitendinosus/gracillis grafts) comparing manually versus mechanically tensioned grafts (using a tensioning device).
Knees requiring ACL-Anterior Cruciate Ligament reconstruction
Queensland Health50 enrolled1 locationACTRN12606000389505