Reconstruction Clinical Trials

127 recruitingLast updated: June 18, 2026

There are 127 actively recruiting reconstruction clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4. Top locations include New York, New York, United States, Houston, Texas, United States, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Reconstruction Trials at a Glance

127 actively recruiting trials for reconstruction are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 78 trials, with the heaviest enrollment activity in New York, Houston, and Chicago. Lead sponsors running reconstruction studies include Stanford University, Chris O'Brien Lifehouse, and Arthrex, Inc..

Browse reconstruction trials by phase

Treatments under study

About Reconstruction Clinical Trials

Looking for clinical trials for Reconstruction? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Reconstruction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Reconstruction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 127 trials

Recruiting
Not Applicable

Tourniquet vs. Dual-flow Arthroscopy Sheath in Anterior Cruciate Ligament (ACL) Reconstruction

Anterior cruciate ligament reconstruction
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer128 enrolled3 locationsNCT06819696
Recruiting
Not Applicable

Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch

Reconstruction SurgeryAirway RemodelingTrachea Diseases
National Taiwan University Hospital10 enrolled2 locationsNCT06935110
Recruiting
Not Applicable

Comparison of Double-tract and Tubular Gastric Anastomosis in Proximal Gastric Cancer

Gastric Cancer (GC)Double-tract ReconstructionTubular Gastric Anastomosis
Qilu Hospital of Shandong University52 enrolled1 locationNCT07635836
Recruiting
Not Applicable

Effectiveness and Safety of OviTex® PRS in Breast Reconstruction

Breast Reconstruction
Tela Bio Inc235 enrolled2 locationsNCT07135596
Recruiting
Phase 3

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

Breast Reconstruction
AbbVie264 enrolled22 locationsNCT06575192
Recruiting
Not Applicable

Evaluation of Wellbeing and Patient Reported Outcomes After Open vs Robotic Mastectomy With DIEP Reconstruction

Breast ReconstructionDIEP Flap Breast ReconstructionBreast Cancer, Breast Neoplasms+1 more
Beaumont Hospital250 enrolled1 locationNCT07230535
Recruiting
Not Applicable

Feasibility and Safety of Single-Port Robotic-Assisted Deep Inferior Epigastric Pedicle Flap Harvest

DIEP Flap Breast Reconstruction
Vanderbilt University Medical Center4 enrolled1 locationNCT07222514
Recruiting
Not Applicable

Pulsed Lavage in Implant-Based Breast Reconstruction

Breast Reconstruction
University of Alabama at Birmingham62 enrolled1 locationNCT05585710
Recruiting
Not Applicable

Hyperbaric Oxygen Therapy to Improve Autologous Fat Graft Intake in Irradiated Breast

Breast ReconstructionHyperbaric Oxygen TherapyLipofilling
University Hospital, Geneva16 enrolled1 locationNCT07140198
Recruiting
Not Applicable

Prospective Evaluation of Silk Fibroin Incision Dressings in ACL Reconstruction

Anterior cruciate ligament reconstruction
NYU Langone Health100 enrolled1 locationNCT07217613
Recruiting

Post-market Surveillance Study to Evaluate the Quality of Life and the Safety and Effectiveness of the TIGR® Matrix After Reconstructive Breast Surgery

Implant Based Breast Reconstruction
AWOgyn135 enrolled5 locationsNCT06511167
Recruiting
Not Applicable

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

Anterior Cruciate Ligament Reconstruction RehabilitationQuadriceps Muscle Function
Arcadia University42 enrolled1 locationNCT07128602
Recruiting
Not Applicable

Effectiveness of Stimulation on the Sciatic Nerve in ACLR

Anterior Cruciate Ligament Reconstruction Rehabilitation
Universidad de Murcia62 enrolled1 locationNCT07569796
Recruiting
Not Applicable

Analysis Of Knee Joint Of Patients With Anterior Cruciate Ligament Injury Undergoing Physiotherapy After Two Different Surgical Techniques: A Randomized Clinical Trial.

Anterior Cruciate Ligament (ACL) TearAnterior Cruciate Ligament Reconstruction Rehabilitation
Universidade Estadual de Londrina20 enrolled3 locationsNCT06809920
Recruiting
Not Applicable

ACL Reconstruction Rehabilitation With Exercise and Psychological Support

Anterior Cruciate Ligament Reconstruction Rehabilitation
HealthPartners Institute60 enrolled1 locationNCT06991192
Recruiting
Not Applicable

Acellular Dermal Matrix Investigation in Breast Reconstruction

Breast Reconstruction
RTI Surgical467 enrolled13 locationsNCT06456554
Recruiting
Phase 4

Sufentanil Infusion vs Intravenous Methadone for Postoperative Analgesia Following Head and Neck Dissection With Free Flap or Rotational Reconstruction

Free Flap Reconstruction
Indiana University128 enrolled1 locationNCT06784999
Recruiting

Evaluation of Safety of Acellular Dermal Matrix(ADM) in Breast Reconstruction

Breast Cancer FemaleBreast Reconstruction
DOF Inc.120 enrolled1 locationNCT06555614
Recruiting
Not Applicable

Clinical Evaluation of Different Treatments for Interdental Black Triangles

Papilla ReconstructionBlack Triangles Syndrome (BTS)
Ain Shams University30 enrolled1 locationNCT07548203
Recruiting

Clinical and Biomechanical Outcomes of Anterior Cruciate Ligament (ACL) Reconstruction Associated With Lateral Extra-articular Tenodesis (LET)

ACL reconstructionACL InjuriesTenodesis
Stefano Zaffagnini51 enrolled1 locationNCT07049484