Phase 3 Reduced Ejection Fraction Clinical Trials

8 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 18 of 8 trials

Recruiting
Phase 3

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

ObesityHeart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection Fraction
Amgen5,056 enrolled596 locationsNCT07037459
Recruiting
Phase 3

Selenium Intervention Registry Randomized Trial in Heart Failure

Heart FailureHeart Failure and Reduced Ejection FractionHeart Failure and Preserved Ejection Fraction+3 more
Skane University Hospital4,326 enrolled11 locationsNCT07543562
Recruiting
Phase 2Phase 3

Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy

Heart Failure With Reduced Ejection FractionHeart Rhythm Disorder
Herlev and Gentofte Hospital348 enrolled1 locationNCT06128980
Recruiting
Phase 3

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Heart FailureHeart Failure With Reduced Ejection Fraction
Cytokinetics1,800 enrolled183 locationsNCT06736574
Recruiting
Phase 3

The Effect of Sacubitril/valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients with Ischemic Heart Failure with Mid-range Ejection Fraction

Heart Failure with Moderately Reduced Ejection Fraction
John Paul II Hospital, Krakow666 enrolled1 locationNCT05508035
Recruiting
Phase 3

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure

Heart FailureCardiovascular DiseasesHypertension+5 more
Pulnovo Medical (Wuxi) Co., Ltd.264 enrolled1 locationNCT05824923
Recruiting
Phase 2Phase 3

Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure

ObesityWeight LossHeart Failure With Reduced Ejection Fraction+1 more
Jens D Hove, MD,PHD100 enrolled1 locationNCT06423599
Recruiting
Phase 3

S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction

Chronic Heart Failure With Reduced Ejection Fraction
Shenzhen People's Hospital5 enrolled1 locationNCT05553886