Phase 1 Refractory Melanoma Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Stage IIIA Uterine Corpus Cancer AJCC v8+35 more

M.D. Anderson Cancer Center54 enrolled1 locationNCT05039801

Recruiting

Phase 1

Phase 1 Dose Escalation and Expansion Study of PRAME T Cell Receptor (TCR) Engineered NK Cells in Participants With Recurrent and/or Refractory Melanoma (PRAMETIME-Mel)

Refractory MelanomaPhase 1Recurrent Melanoma

M.D. Anderson Cancer Center39 enrolled1 locationNCT06660420

Recruiting

Phase 1Phase 2

DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

Refractory Melanoma

Diakonos Oncology Corporation35 enrolled2 locationsNCT07288112