Phase 2 Renal Disease Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 113 of 13 trials

Recruiting
Phase 2

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

End Stage Renal Disease on DialysisHyperphosphatemiaChronic Kidney Disease Requiring Chronic Dialysis
R1 Therapeutics168 enrolled26 locationsNCT06712654
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled1 locationNCT07224763
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled2 locationsNCT06878560
Recruiting
Phase 2Phase 3

Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile

End Stage Renal Disease
Roberto Gedaly78 enrolled1 locationNCT03321656
Recruiting
Phase 2

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

End Stage Renal DiseasePrimary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company28 enrolled18 locationsNCT04580420
Recruiting
Phase 2

Safety and Efficacy of Empagliflozin in Hemodialysis

End Stage Renal Disease
NYU Langone Health60 enrolled2 locationsNCT05786443
Recruiting
Phase 1Phase 2

To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of KN060 in ESRD Dialysis Patients

End-Stage Renal Disease Requiring Haemodialysis
Suzhou Alphamab Co., Ltd.12 enrolled1 locationNCT07201467
Recruiting
Phase 2

Activated Charcoal Use in Chronic Kidney Disease Patients

End Stage Renal Disease (ESRD)CKD 5D, HemodialysisCKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
Mansoura University40 enrolled1 locationNCT06906874
Recruiting
Phase 2

Empagliflozin on Residual Kidney Function in Incident Peritoneal Dialysis Patients

End Stage Renal Disease on DialysisPeritoneal Dialysis ComplicationResidual Kidney Function+1 more
Chinese University of Hong Kong48 enrolled1 locationNCT06483074
Recruiting
Phase 1Phase 2

CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk

Kidney FailureEnd Stage Renal DiseaseKidney Tumor+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053462
Recruiting
Phase 1Phase 2

Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients

Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 1Phase 2

Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients

Depression Anxiety DisorderKidney Failure, ChronicAnemia in End Stage Renal Disease
Mansoura University46 enrolled1 locationNCT06917950
Recruiting
Phase 1Phase 2

The Effect of Gum Arabic (GA) on Residual Renal Function in Adult Dialysis Patients in Abu Dhabi

End Stage Renal Disease (ESRD)
Abu Dhabi Health Services Company40 enrolled1 locationNCT06836206