Phase 1 Retinopathy Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1Phase 2

Oral Metformin for Treatment of ABCA4 Retinopathy

Retinal DegenerationRetinal DystrophyStargardt Disease+1 more
National Eye Institute (NEI)56 enrolled2 locationsNCT04545736
Recruiting
Phase 1

Safety, PK and PD of FLQ-101 in Premature Neonates

Retinopathy of Prematurity (ROP)
FELIQS INC.18 enrolled1 locationNCT07093255
Recruiting
Phase 1Phase 2

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

rhegmatogenous retinal detachmentProliferative Vitreoretinopathy
Massachusetts Eye and Ear Infirmary48 enrolled1 locationNCT06033703
Recruiting
Phase 1

MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema

Diabetic RetinopathyDiabetic Macular EdemaMacular Edema+2 more
Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.45 enrolled3 locationsNCT04187443
Recruiting
Phase 1Phase 2

Evaluating a New Peptide Therapy for Retinal Diseases: AMD, Diabetic Retinopathy, and Dystrophies

Retinitis pigmentosa (RP)Age-Related Macular DegenerationDiabetic Retinopathy
Ace Cells Lab Limited100 enrolled2 locationsNCT06787482
Recruiting
Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for NAION

Retinitis PigmentosaMacular DegenerationDiabetic Retinopathy+3 more
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled2 locationsNCT05147701
Recruiting
Phase 1

A Study Intravitreal THN391 in Diabetic Macular Oedema Secondary to Non-Proliferative Diabetic Retinopathy.

Diabetic RetinopathyDiabetic Macular Edema
Therini Bio Pty Ltd21 enrolled2 locationsNCT06701721
Recruiting
Phase 1

Pharmacokinetics and Safety of Dexamethasone Eye Drops in Preterm Infants

Retinopathy of Prematurity
Region Skane15 enrolled2 locationsNCT05387941