Retinopathy Clinical Trials

117 recruitingLast updated: June 18, 2026

There are 117 actively recruiting retinopathy clinical trials across 46 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1, Phase 4. Top locations include Palo Alto, California, United States, Chicago, Illinois, United States, Indianapolis, Indiana, United States. Updated daily from ClinicalTrials.gov.


Retinopathy Trials at a Glance

117 actively recruiting trials for retinopathy are listed on ClinicalTrialsFinder across 6 cities in 46 countries. The largest study group is Not Applicable with 38 trials, with the heaviest enrollment activity in Palo Alto, Chicago, and Indianapolis. Lead sponsors running retinopathy studies include Jaeb Center for Health Research, Duke University, and Second Affiliated Hospital, School of Medicine, Zhejiang University.

Browse retinopathy trials by phase

Treatments under study

About Retinopathy Clinical Trials

Looking for clinical trials for Retinopathy? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Retinopathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Retinopathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 117 trials

Recruiting

Biomarker of Diabetic Retinopathy

Diabetic Retinopathy
Indiana University192 enrolled3 locationsNCT05079399
Recruiting
Not Applicable

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Diabetic RetinopathyHypertension,EssentialRetinal Vein Occlusion+1 more
Johns Hopkins University1,050 enrolled1 locationNCT04505618
Recruiting
Phase 2Phase 3

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

Diabetic Retinopathy
AbbVie576 enrolled6 locationsNCT07592273
Recruiting
Phase 2

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

Intraventricular hemorrhageChronic lung disease of prematurityBronchopulmonary Dysplasia+1 more
OHB Neonatology Ltd.338 enrolled72 locationsNCT03253263
Recruiting
Not Applicable

Village-Integrated Eye Worker Trial II

Age-Related Macular DegenerationDiabetic RetinopathyGlaucoma
University of California, San Francisco60,200 enrolled1 locationNCT03752840
Recruiting

National Eye Institute Biorepository for Retinal Diseases

Age-Related Macular DegenerationDiabetic RetinopathyRetinal Disease+2 more
National Eye Institute (NEI)650 enrolled1 locationNCT01496625
Recruiting
Phase 4

To Evaluate the Efficacy and Safety of N-acetyl Cysteine Administration in Patients With Diabetic Retinopathy

Diabetic Retinopathy (DR)
Ain Shams University76 enrolled2 locationsNCT07634991
Recruiting
Not Applicable

Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment

Age related macular degeneration (AMD)Diabetic Retinopathy (DR)Retinal Detachment
Fondazione G.B. Bietti, IRCCS260 enrolled1 locationNCT07500324
Recruiting
Not Applicable

the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy

Central Serous Chorioretinopathy
Second Affiliated Hospital, School of Medicine, Zhejiang University400 enrolled1 locationNCT06527326
Recruiting
Not Applicable

Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

Retinopathy of Prematurity
Duke University236 enrolled2 locationsNCT04995341
Recruiting

An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)

Preterm infantsRetinopathy of Prematurity
Bayer200 enrolled1 locationNCT06315556
Recruiting
Phase 3

Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

Proliferative Diabetic Retinopathy (PDR)
Jaeb Center for Health Research426 enrolled27 locationsNCT06790784
Recruiting
Phase 3

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

Visual ImpairmentRadiation Retinopathy
Jaeb Center for Health Research600 enrolled23 locationsNCT05844982
Recruiting
Not Applicable

Video-based Patient Education Intervention for Diabetic Eye Screening in Latinx Communities

Diabetic Retinopathy
University of Wisconsin, Madison1,526 enrolled1 locationNCT06257082
Recruiting
Phase 1Phase 2

Oral Metformin for Treatment of ABCA4 Retinopathy

Retinal DegenerationRetinal DystrophyStargardt Disease+1 more
National Eye Institute (NEI)56 enrolled2 locationsNCT04545736
Recruiting
Not Applicable

Early Vitrectomy vs PRP in Early Proliferative Diabetic Retinopathy

Proliferative Diabetic Retinopathy (PDR)
Xiamen Ophthalmology Center Affiliated to Xiamen University100 enrolled6 locationsNCT07586787
Recruiting

Adaptive Optics Imaging of Outer Retinal Diseases

Age-Related Macular DegenerationRetinal DegenerationRetinitis Pigmentosa+7 more
Food and Drug Administration (FDA)100 enrolled2 locationsNCT05355415
Recruiting
Phase 2

Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity

Retinopathy of Prematurity
University of Zurich276 enrolled3 locationsNCT03083431
Recruiting
Not Applicable

Strategies for Improving Linkage-to-Care After Eye Disease Screening

Age-Related Macular DegenerationDiabetic RetinopathyGlaucoma
University of California, San Francisco3,000 enrolled1 locationNCT06943599
Recruiting
Not Applicable

Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies

Diabetic RetinopathyRetinal Vein Occlusion
CHU de Reims120 enrolled1 locationNCT03680794