Phase 1 Scleroderma Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1
Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs）
Rheumatoid ArthritisSclerodermaSystemic Lupus Erythematosus
Shenzhen MagicRNA Biotechnology Co., Ltd30 enrolled1 locationNCT06801119
Recruiting
Phase 1Phase 2
RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
SclerodermaSystemic Sclerosis
Cabaletta Bio12 enrolled10 locationsNCT06328777
Recruiting
Phase 1
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Completed
Phase 1
A clinical study to compare the safety and tolerability of two formulations of a new Systemic Sclerosis drug in Healthy Participants - Part B
Systemic sclerosis
Scleroderma
Certa Therapeutics Pty Ltd33 enrolled1 locationACTRN12625000744459
Completed
Phase 1
A clinical study to compare the safety and tolerability of two formulations of a new Systemic Sclerosis drug in Healthy Participants - Part A
SclerodermaSystemic Sclerosis
Certa Therapeutics Pty Ltd12 enrolled1 locationACTRN12625000733471
Recruiting
Phase 1
TENS in Scleroderma
SclerodermaGastroparesisSystemic Sclerosis (SSc)
University of Michigan16 enrolled1 locationNCT06646913
Recruiting
Phase 1
Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease
DermatomyositisSystemic SclerodermaAnti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis+2 more
Chongqing Precision Biotech Co., Ltd24 enrolled1 locationNCT06056921