Phase 3 Soft Tissue Clinical Trials
16 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–16 of 16 trials
Recruiting
Phase 3
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
Metastatic Dedifferentiated LiposarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more
National Cancer Institute (NCI)365 enrolled251 locationsNCT06422806
Recruiting
Phase 3
Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)
Soft Tissue Sarcoma
Polaris Group300 enrolled31 locationsNCT05712694
Recruiting
Phase 3
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma
Soft Tissue Sarcoma
Institut Claudius Regaud600 enrolled19 locationsNCT04307277
Recruiting
Phase 3
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
Soft Tissue SarcomaLeiomyosarcomaSynovial Sarcoma+1 more
Advenchen Laboratories, LLC325 enrolled24 locationsNCT03016819
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
MalignancyGastric CancerSoft Tissue Sarcoma+8 more
Cancer Research UK30 enrolled17 locationsNCT06988475
Recruiting
Phase 3
Effectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in Children
Soft tissue injuries
Cairo University100 enrolled1 locationNCT05448807
Recruiting
Phase 3
tislelizUMaB in canceR Patients With molEcuLar residuaL Disease
Soft Tissue SarcomaLung CancerCancer+2 more
Gustave Roussy, Cancer Campus, Grand Paris717 enrolled1 locationNCT06332274
Recruiting
Phase 3
tTF-NGR Randomized Study - STS
Soft Tissue Sarcoma
Universität Münster126 enrolled9 locationsNCT05597917
Recruiting
Phase 3
Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients
Metastatic Soft Tissue SarcomaAdvanced Soft Tissue Sarcoma
UNICANCER214 enrolled1 locationNCT04757337
Recruiting
Phase 3
A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma
Soft Tissue Sarcoma
Philogen S.p.A.102 enrolled28 locationsNCT04650984
Recruiting
Phase 2Phase 3
Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors
SarcomaOsteosarcomaSarcoma of Bone+2 more
Blokhin's Russian Cancer Research Center50 enrolled1 locationNCT05057130
Recruiting
Phase 3
Use of GnRHa During Chemotherapy for Fertility Protection
Breast Cancer FemaleSoft Tissue SarcomaAcute Leukemia+3 more
Kenny Rodriguez-Wallberg500 enrolled17 locationsNCT05328258
Completed
Phase 3Phase 4
Fiji Northern Division Ivermectin Mass Drug Administration for Scabies Trial
Post streptococcal glomerulonephritisInvasive group A streptococcal infectionsSkin and soft tissue infections+3 more
Murdoch Children's Research Insititute135,000 enrolled1 locationACTRN12618000461291
Terminated
Phase 3
Hyperbaric Oxygen Therapy for Radiation Induced Xerostomia (Dry Mouth)
Soft tissue radiation injury to salivary glands (xerostomia)Head and Neck Cancer
Dr S Sherlock60 enrolled1 locationACTRN12612000084886
Recruiting
Phase 3
A Pivotal Trial to Determine the Efficacy and Safety of AP23573 when Administered as Maintenance Therapy to Patients with Metastatic Soft Tissue or Bone Sarcomas.
Metastatic soft tissue or bone sarcomas
ARIAD Pharmaceuticals, Inc.650 enrolled26 locationsACTRN12608000214336
Completed
Phase 2Phase 3
Hyperbaric Oxygen in Lower Limb Trauma
Acute open fractures of the tibia with associated severe soft tissue injuryOutcomesTrauma+2 more
Alfred Health120 enrolled11 locationsACTRN12607000559415