Phase 1 Solid Malignancies Clinical Trials
14 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–14 of 14 trials
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Non-small Cell Lung Cancer (NSCLC)Pancreatic Ductal Adenocarcinoma (PDAC)Advanced Solid Malignancies+1 more
Bristol-Myers Squibb252 enrolled8 locationsNCT07223047
Recruiting
Phase 1
Controlled Cold Exposure Combined With PD-1/PD-L1 Immunotherapy in Solid Tumors (NIVALIS)
Solid TumorsImmunotherapyCold Exposure+1 more
West China Hospital24 enrolled1 locationNCT07538479
Recruiting
Phase 1
Phase 1 Open Label Trial of MST-0312 Alone and in Combination in Subjects With Solid Malignancies
Solid Malignancies
Mestag Therapeutics Limited157 enrolled6 locationsNCT07610941
Recruiting
Phase 1
A Phase 1 Study of SKB571 in Subjects With Advanced Solid Tumors
Solid Malignancies
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.138 enrolled15 locationsNCT06725381
Recruiting
Phase 1Phase 2
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Advanced Solid Malignancies
AstraZeneca695 enrolled32 locationsNCT05417594
Recruiting
Phase 1
A Phase 1 Study of IM-1021 in Participants With Advanced Cancer
Hematologic MalignanciesSolid Malignancies
Immunome, Inc.117 enrolled13 locationsNCT06823167
Recruiting
Phase 1
Phase I Study of the Safety, Tolerability, and Efficacy of an Engineered Mitochondrial Vaccine in Advanced Solid Tumors
Advanced Solid MalignanciesAdvanced Solid Tumor Malignancies
West China Hospital12 enrolled1 locationNCT06927297
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Efficacy of BC2027 in Patients With Advanced Solid Malignancies
Advanced Solid Malignancies
Biocity Biopharmaceutics Co., Ltd.180 enrolled1 locationNCT07368478
Recruiting
Phase 1Phase 2
A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies
Solid Malignancies
Carrick Therapeutics Limited50 enrolled6 locationsNCT06600789
Recruiting
Phase 1
Safety and Tolerability of CMAB017 In Patients With Advanced Solid Tumors
Solid Malignancies
Taizhou Mabtech Pharmaceutical Co.,Ltd55 enrolled1 locationNCT06933069
Recruiting
Phase 1Phase 2
Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies
Advanced Solid Malignancies
Georgiamune Inc111 enrolled11 locationsNCT06028074
Recruiting
Phase 1Phase 2
A Phase I/II Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects with Advanced Solid Tumors
Advanced Solid TumorAdvanced Solid Malignancies
Zhuhai Yufan Biotechnologies Co., Ltd267 enrolled5 locationsNCT05315167
Completed
Phase 1
Phase I accelerated dose-escalation study of CYT997 given as an oral capsule every two weeks in patients with advanced solid tumours
Cancer - solid malignancies that are metastatic or unresectable
Cytopia Research Pty Ltd15 enrolled1 locationACTRN12606000520538
Completed
Phase 1
Phase I dose-escalation study for CYT997
Cancer - solid malignancies that are metastatic or unresectable
Cytopia Research Pty Ltd24 enrolled1 locationACTRN12605000793617