Phase 2 Solid Tumour Clinical Trials
28 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 28 trials
Recruiting
Phase 2
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
Solid Tumours
Boehringer Ingelheim430 enrolled88 locationsNCT06581432
Recruiting
Phase 2
A Phase II Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumour[Substudy 04]
Advanced Solid Tumour
Nanjing Leads Biolabs Co.,Ltd110 enrolled6 locationsNCT07390383
Recruiting
Phase 1Phase 2
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
Solid Tumours
AstraZeneca180 enrolled18 locationsNCT07446855
Recruiting
Phase 1Phase 2
A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors
Solid Tumours
Bristol-Myers Squibb315 enrolled19 locationsNCT07160725
Recruiting
Phase 2
A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 02(BTC&HCC)]
Advanced Solid Tumour
Nanjing Leads Biolabs Co.,Ltd140 enrolled6 locationsNCT07111546
Recruiting
Phase 2
A Phase II Clinical Study of LBL-024 Combination Therapy in Patients With Advanced Solid Tumour[Substudy 03(ESCC)]
Advanced Solid Tumour
Nanjing Leads Biolabs Co.,Ltd110 enrolled7 locationsNCT07331155
Recruiting
Phase 1Phase 2
Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors
Advanced Solid Tumours
Pyxis Oncology, Inc220 enrolled15 locationsNCT06795412
Recruiting
Phase 2
A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]
Advanced Solid Tumour
Nanjing Leads Biolabs Co.,Ltd230 enrolled24 locationsNCT06783647
Recruiting
Phase 2
Hybrid Arc Palliative Radiation Therapy (HART): A Single Arm Phase II Trial
Palliative RadiotherapyMetastatic Cancer (Different Solid Tumour Types)
University of Vermont Medical Center103 enrolled1 locationNCT06778408
Recruiting
Phase 1Phase 2
A Phase 1/2, First-in-Human Study On ODM-212 In Subjects With Selected Advanced Solid Tumours
Solid Tumours
Orion Corporation, Orion Pharma315 enrolled1 locationNCT06725758
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations
Ovarian NeoplasmsColorectal NeoplasmsUrinary Bladder Neoplasm+8 more
Cancer Research UK30 enrolled27 locationsNCT05786716
Recruiting
Phase 2Phase 3
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol
Haematological MalignancySolid Tumour
Cancer Research UK825 enrolled27 locationsNCT05722886
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition
MalignancyMelanomaCancer+7 more
Cancer Research UK30 enrolled27 locationsNCT05770102
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.
MalignancyMelanomaCancer+8 more
Cancer Research UK30 enrolled27 locationsNCT05770544
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers
CancerRenal Cell CarcinomaLymphoma+8 more
Cancer Research UK30 enrolled27 locationsNCT05770037
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
MalignancyGastric CancerSoft Tissue Sarcoma+8 more
Cancer Research UK30 enrolled17 locationsNCT06988475
Recruiting
Phase 1Phase 2
A Study of LM-168 as a Single Agent or in Combination With Toripalimab in Subjects With Advanced Solid Tumours
Advanced Solid Tumours
LaNova Medicines Limited87 enrolled6 locationsNCT06868199
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Initial Efficacy of JS212 in Subjects With Advanced Malignant Solid Tumour
Advanced Malignant Solid Tumours
Shanghai Junshi Bioscience Co., Ltd.374 enrolled1 locationNCT06888830
Recruiting
Phase 1Phase 2
Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB41 in Adult Patients with Advanced Malignant Solid Tumours.
Advanced Malignant Solid Tumours
Sinocelltech Ltd.441 enrolled1 locationNCT06600022
Recruiting
Phase 2
ADC-induced Neurotoxicity Treated With Duloxetine
Solid Tumour
Fudan University37 enrolled1 locationNCT06551051