Phase 2 SON Clinical Trials

101 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 101 trials

Recruiting
Phase 1Phase 2

Personalized Neoantigen Peptide Vaccines for Solid Tumors

Solid TumorsAdvanced CancerRecurrent Cancer+2 more
Seqker Biosciences, Inc.10 enrolled1 locationNCT07002203
Recruiting
Phase 2

Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease

Parkinson Disease
Gateway Institute for Brain Research56 enrolled4 locationsNCT05266417
Recruiting
Phase 2Phase 3

Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of VG081821AC Tablets in Patients With Early to Mid-stage Parkinson's Disease

Parkinson Disease (PD)
Zhejiang Vimgreen Pharmaceuticals, Ltd.152 enrolled1 locationNCT07725562
Recruiting
Phase 2

A Study of Avutometinib (VS-6766) and Defactinib in People With Mesonephric Gynecologic Cancer

Mesonephric Gynecologic Cancer
Memorial Sloan Kettering Cancer Center40 enrolled7 locationsNCT05787561
Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Phase 2

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

StrokeParkinson DiseaseDysphagia
Purdue University120 enrolled2 locationsNCT06638944
Recruiting
Phase 2

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

Parkinson Disease
Appello Pharmaceuticals, Inc.150 enrolled30 locationsNCT07432958
Recruiting
Phase 2

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

DepressionParkinson's Disease (PD)
Yale University40 enrolled1 locationNCT07610369
Recruiting
Phase 1Phase 2

Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)

Parkinson's Disease (PD)
EicOsis Human Health Inc.18 enrolled1 locationNCT07142044
Recruiting
Phase 2Phase 3

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

Parkinson Disease
Biohaven Therapeutics Ltd.550 enrolled15 locationsNCT06976268
Recruiting
Phase 2

Combined Gastrointestinal Decontamination in Acute Severe Poisoning

Severe Poisoning With Cardiotropic or Psychotropic DrugAdmission to Intensive Care
Assistance Publique - Hôpitaux de Paris200 enrolled1 locationNCT07201311
Recruiting
Phase 2

Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort

Magnetic Resonance ImagingCerebrovascular Circulation
University of Wisconsin, Madison36 enrolled1 locationNCT06629090
Recruiting
Phase 2

A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockade

Fentanyl OverdoseFentanyl Poisoning
Clear Scientific, Inc.16 enrolled1 locationNCT07459166
Recruiting
Phase 2

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Parkinson DiseaseParkinsonParkinson Disease, Idiopathic+2 more
Neuron23 Inc.150 enrolled70 locationsNCT06680830
Recruiting
Phase 2

18F-mFBG Cardiac Uptake With Lewy Body Dementia

Lewy Body Dementia (LBD)Parkinson Disease (PD)
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)20 enrolled1 locationNCT07176286
Recruiting
Phase 2

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

Parkinson Disease
AskBio Inc127 enrolled46 locationsNCT06285643
Recruiting
Phase 2

A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's Disease

Parkinson Disease
Cambridge University Hospitals NHS Foundation Trust36 enrolled1 locationNCT07157735
Recruiting
Phase 2

Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder

Borderline Personality Disorder
Yale University150 enrolled1 locationNCT06446765
Recruiting
Phase 2

D-SPARK: A Clinical Trial of D-Serine for Modifying Parkinson's Disease Progression

Parkinson's DiseaseParkinson Disease (PD)
Haukeland University Hospital100 enrolled11 locationsNCT07312110
Recruiting
Phase 1Phase 2

A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder

Borderline personality disorder (BPD)
Mclean Hospital20 enrolled1 locationNCT07460947