Spastic Clinical Trials

138 recruitingLast updated: June 18, 2026

There are 138 actively recruiting spastic clinical trials across 35 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1, Phase 4. Top locations include Dallas, Texas, United States, New York, New York, United States, Lahore, Punjab Province, Pakistan. Updated daily from ClinicalTrials.gov.


Spastic Trials at a Glance

138 actively recruiting trials for spastic are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 80 trials, with the heaviest enrollment activity in Dallas, New York, and Lahore. Lead sponsors running spastic studies include Universitaire Ziekenhuizen KU Leuven, Cairo University, and Riphah International University.

Treatments under study

About Spastic Clinical Trials

Looking for clinical trials for Spastic? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Spastic trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Spastic clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 138 trials

Recruiting
Not Applicable

Trial to Test the Effectiveness of Vibrotactile Stimulation for Lower Limb Spasticity

Lower limb spasticity
Weill Medical College of Cornell University25 enrolled1 locationNCT07447934
Recruiting

Evaluation of Patients With HAM/TSP

HTLV-I InfectionTropical Spastic Paraparesis
National Institute of Neurological Disorders and Stroke (NINDS)750 enrolled1 locationNCT00001778
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

Multiple Sclerosis Spasticity
Celgene200 enrolled54 locationsNCT06782490
Recruiting
Not Applicable

Impact of rTMS Combined With Neurorehabilitation on Lower Extremity Motor Function and Spasticity in Children With Spastic Diplegic Cerebral Palsy

Cerebral Palsy (CP)Transcranial Magnetic StimilationDiplegic Cerebral Palsy With Spasticity+1 more
Ankara City Hospital Bilkent20 enrolled1 locationNCT07488429
Recruiting
Not Applicable

Robot-assisted Versus Conventional Physical Therapy for Hand in Sub-acute Stroke

Upper-limb motor impairmentStrokeSpastic Hemiplegia
Montiha Azeem30 enrolled1 locationNCT07615569
Recruiting
Phase 3

PREcision MEDicine In Achalasia (PREMEDIA)

Type I AchalasiaType II AchalasiaEGJ Outflow Obstruction Without Spastic/Hypercontractile Features
Northwestern University372 enrolled13 locationsNCT07293650
Recruiting

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

Type III AchalasiaEGJ Outflow Obstruction With Spastic/Hypercontractile FeaturesJackhammer Esophagus+1 more
Northwestern University200 enrolled13 locationsNCT07293689
Recruiting
Not Applicable

Sensory Walkway and Gait in Children With Diplegic Cerebral Palsy

Spastic Diplegic Cerebral Palsy
Cairo University44 enrolled1 locationNCT07595744
Recruiting

Evaluation of Brain MRI Changes in Cerebral Palsy Patients

Cerebral PalsySpastic DiplegiaSpastic Quadriplegia+1 more
Columbia University30 enrolled1 locationNCT07433647
Recruiting
Not Applicable

Feasibility Nutritional Supplements for Muscle Growth in CP

Spastic Cerebral Palsy
Universitaire Ziekenhuizen KU Leuven5 enrolled1 locationNCT06044168
Recruiting

3D-Microscopic Muscle Architecture in Cerebral Palsy

Spastic Cerebral Palsy
Universitaire Ziekenhuizen KU Leuven130 enrolled1 locationNCT06584851
Recruiting

Genetic and Physical Study of Childhood Nerve and Muscle Disorders

Muscular DystrophiesMuscle MyopathiesHereditary Spastic Paraplegias+2 more
National Institute of Neurological Disorders and Stroke (NINDS)9,300 enrolled1 locationNCT01568658
Recruiting
Phase 1Phase 2

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.

Spasticity
Ipsen240 enrolled81 locationsNCT04752774
Recruiting
Not Applicable

tSCS in Children and Young People With HCP

Cerebral Palsy Spastic Hemiplegic
University of Leeds18 enrolled1 locationNCT07247812
Recruiting

Muscle-tendon Pathology and Metabolic Dysregulation in CP

Cerebral Palsy, Spastic
University of Graz50 enrolled1 locationNCT06330922
Recruiting

Botulinum Neurotoxin for Children With CP: a Delicate Balance Between Clinical Benefits and Muscular Harm

Spastic Cerebral Palsy (sCP)
Universitaire Ziekenhuizen KU Leuven51 enrolled1 locationNCT06991725
Recruiting
Not Applicable

Pilot Study on Muscle, Tendon, and Neural Changes Post-Botulinum Toxin Injections in Post-stroke Spastic Equinovarus

StrokeSpasticityEquinovarus Foot
Universitaire Ziekenhuizen KU Leuven12 enrolled1 locationNCT06767631
Recruiting
Not Applicable

Neuromodulation to Enhance Motor Function in HSP

Hereditary Spastic Paraplegia
Rahul Sachdeva15 enrolled1 locationNCT07417943
Recruiting
Phase 3

Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.

Hereditary Spastic Paraplegia Type 50
Elpida Therapeutics SPC24 enrolled2 locationsNCT06692712
Recruiting
Not Applicable

Cryoneurolysis for Spasticity Treatment: Long-term Clinical Outcomes and Mechanisms in the Central Nervous System

Spasticity as Sequela of Stroke
Sue Peters25 enrolled1 locationNCT06958289