Phase 2 Steatotic Liver Disease Clinical Trials

8 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 18 of 8 trials

Recruiting
Phase 2

A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

HIV (Human Immunodeficiency Virus)MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Naga P. Chalasani120 enrolled10 locationsNCT07143968
Recruiting
Phase 2

Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial

MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)

Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
Regeneron Pharmaceuticals132 enrolled3 locationsNCT06836609
Recruiting
Phase 1Phase 2

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Healthy VolunteersMetabolic dysfunction–associated steatotic liver disease (MASLD)
Regeneron Pharmaceuticals172 enrolled6 locationsNCT05648214
Recruiting
Phase 2

Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study)

Hepatic SteatosisNonalcoholic SteatohepatitisMetabolic-Associated Steatotic Liver Disease
Hudson Biotech120 enrolled1 locationNCT07481734
Recruiting
Phase 1Phase 2

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

Liver DiseasesCirrhosis, LiverDecompensated Liver Cirrhosis+5 more
Resolution Therapeutics Limited30 enrolled14 locationsNCT06823713
Recruiting
Phase 2

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

ObesityOverweight (BMI > 25)MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Washington University School of Medicine40 enrolled1 locationNCT07097506
Recruiting
Phase 2

Aspirin for Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease

Metabolic Dysfunction-Associated Steatotic Liver Disease
Taichung Veterans General Hospital120 enrolled1 locationNCT06935994