Phase 3 STI Clinical Trials

197 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 197 trials

Recruiting
Phase 3

Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults

Nasal congestionCommon Cold/Flunasal obstruction
Brainfarma Industria Química e Farmacêutica S/A620 enrolled15 locationsNCT07626437
Recruiting
Phase 3

STOP-PKD: SGLT2-inhibition to Improve Prognosis in Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant
University of Cologne420 enrolled30 locationsNCT07280585
Recruiting
Phase 3

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

Myelodysplastic SyndromeAnemia
Takeda300 enrolled154 locationsNCT07422480
Recruiting
Phase 3

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

Metastatic CancerAdvanced Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc.482 enrolled126 locationsNCT05208047
Recruiting
Phase 3

A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

B-cell Acute Lymphoblastic Leukemia
Memorial Sloan Kettering Cancer Center130 enrolled5 locationsNCT07223021
Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Phase 3

Study of Out of Specification for Tisagenlecleucel

Diffuse Large B Cell LymphomaB-cell Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals200 enrolled53 locationsNCT04094311
Recruiting
Phase 3

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Urinary Bladder NeoplasmsImmune Checkpoint InhibitorsMethotrexate+4 more
AstraZeneca150 enrolled59 locationsNCT06960577
Recruiting
Phase 3

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

Gastrointestinal Neoplasms
GlaxoSmithKline450 enrolled124 locationsNCT07218926
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Rituximab and Mycophenolate Mofetil Combination in Patients With Interstitial Lung Disease Related to Systemic Sclerosis

Interstitial Lung Disease With Systemic Sclerosis
University Hospital, Tours102 enrolled1 locationNCT06549231
Recruiting
Phase 3

A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

Interstitial Lung DiseasesSystemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
Boehringer Ingelheim400 enrolled158 locationsNCT06806592
Recruiting
Phase 3

STI Testing to Enhance PrEP Use in Pregnancy

PregnancySexually Transmitted Infections (STIs)PrEP Adherence
Botswana Harvard AIDS Institute Partnership600 enrolled1 locationNCT06919614
Recruiting
Phase 2Phase 3

Efficacy and Safety of NB003 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

GIST - Gastrointestinal Stromal TumorAdvanced
Ningbo Newbay Technology Development Co., Ltd255 enrolled32 locationsNCT07379047
Recruiting
Phase 3

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

Interstitial Lung DiseasesFamilial Pulmonary FibrosisInterstitial Lung Abnormalities
Boehringer Ingelheim80 enrolled56 locationsNCT07201922
Recruiting
Phase 2Phase 3

Evaluating Smoking Cessation Interventions for PWH in South Africa

Comorbidities and Coexisting ConditionsSmoking CessationHIV
Johns Hopkins University660 enrolled1 locationNCT05413122
Recruiting
Phase 3

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Colorectal NeoplasmsNeoplasms by SiteGastrointestinal Neoplasms+7 more
Pfizer800 enrolled228 locationsNCT07222800
Recruiting
Phase 2Phase 3

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

B-cell Acute Lymphoblastic Leukemia
Merck Sharp & Dohme LLC340 enrolled3 locationsNCT07570173
Recruiting
Phase 3

A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC

Colorectal NeoplasmsNeoplasm MetastasisGastrointestinal Neoplasms+2 more
Sun Yat-sen University280 enrolled1 locationNCT03303495
Recruiting
Phase 2Phase 3

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Interstitial CystitisPainful Bladder SyndromePainful Bladder Syndrome (PBS)
David Sheyn100 enrolled1 locationNCT06096597
Recruiting
Phase 3

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Progressive Pulmonary FibrosisInterstitial Lung Disease
United Therapeutics698 enrolled159 locationsNCT05943535