Phase 1 Streptococcal Infections Clinical Trials
3 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–3 of 3 trials
Recruiting
Phase 1
A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component Strep A Vaccine With Aluminum Hydroxide (Alum) or AS37 in Healthy Young Adults
Streptococcal Infections
GlaxoSmithKline108 enrolled2 locationsNCT07085702
Not Yet Recruiting
Phase 1
A study to compare safety, tolerability, and how the body processes a powdered penicillin injection (Extencilline®) given into the muscle or under the skin in healthy adults
Group A streptococcal infectionsRheumatic heart diseaseSyphilis
The Kids Research Institute Australia15 enrolled1 locationACTRN12625000684426
Completed
Phase 1
How does the absorption of benzathine penicillin G (BPG) used for Group A Streptococcus (GAS) treatment and secondary prophylaxis for rheumatic fever (RF) differ when injected into the fat layer compared to injection in the muscle in healthy adult men?
Group A streptococcal infectionsRheumatic feverSyphilis
Telethon Kids Institute15 enrolled1 locationACTRN12618001435279