Phase 1 Symptoms Clinical Trials
18 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–18 of 18 trials
Recruiting
Phase 1Phase 2
Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause
Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 1
Open-Label Psilocybin Study in Transdiagnostic Population
AnxietyDepression - Major Depressive DisorderPTSD+5 more
Yale University50 enrolled1 locationNCT06442423
Recruiting
Phase 1Phase 2
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
MELAS SyndromeLebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
George Washington University24 enrolled1 locationNCT06792500
Recruiting
Phase 1
Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy
Persisting Symptoms After Concussion
University of Calgary40 enrolled1 locationNCT06615908
Recruiting
Phase 1
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Mild Traumatic Brain InjuryHeadacheBrain Concussion+1 more
State University of New York - Upstate Medical University60 enrolled1 locationNCT06112093
Recruiting
Phase 1
Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis
PsychosisNegative Symptoms With Primary Psychotic Disorder
Bjorn H. Ebdrup46 enrolled1 locationNCT04789915
Recruiting
Phase 1Phase 2
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
Autism Spectrum DisorderGastrointestinal Symptoms
The University of Texas Health Science Center, Houston70 enrolled1 locationNCT03514784
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of tamsulosin tablet against the innovator tamsulosin tablet conducted under fasting condition and at steady state in healthy male and female volunteers.
Tamsulosin is indicated for the relief of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12618001147279
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of tamsulosin tablet against the innovator tamsulosin tablet conducted under fed condition in healthy male and female volunteers.
Tamsulosin is indicated for the relief of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
Zenith Technology Corp Ltd28 enrolled1 locationACTRN12618001051235
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of tamsulosin tablet against the innovator tamsulosin tablet conducted under fasting condition in healthy male and female volunteers.
Tamsulosin is indicated for the relief of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12618000776202
Completed
Phase 1
The effect of a dietary ketone on immunity, tolerability and performance in well-trained, healthy male cyclists.
Systemic symptoms (e.g. dizziness, nausea)Exercise-Induced immunosuppressionGastrointestinal distress
Auckland University of Technology12 enrolled1 locationACTRN12617001347358
Completed
Phase 1
The effect of a dietary ketone on immunity and tolerability in recreationally active, healthy males at rest.
Systemic symptoms (e.g. dizziness, nausea)Exercise-Induced immunosuppressionGastrointestinal distress
Auckland University of Technology6 enrolled1 locationACTRN12617000731392
Completed
Phase 1
Noribogaine Therapy for Relief of Opioid withdrawal, Phase 1B
Symptoms of opioid withdrawal
DemeRx Inc27 enrolled1 locationACTRN12613001064796
Completed
Phase 1
A single dose, randomized, blinded, pilot, comparative assessment of the absorption of a generic formulation of tibolone tablet against the innovator tibolone tablet conducted in healthy female volunteers under fasting conditions
Pilot bioequivalence study conducted in healthy volunteers comparing two formulations of tibolone with no health condition or problem studied.
Although this study is being conducted in healthy volunteers who are not being treated for the condition to which the medicine is used, tibolone belongs to a class of medicines called synthetic steroid hormone drugs and is prescribed for the short-term treatment of symptoms due to natural or surgical menopause.
Zenith Technology Corporation Limited8 enrolled1 locationACTRN12613000943741
Recruiting
Phase 1
A randomised trial comparing the effect of green-lipped mussel and glucosamine in treating osteoarthritis of the knee and assessing if this correlates to the nutraceuticals improving gut integrity
Irritable Bowel SymptomsOsteoarthritis of the knee
The University of Queensland40 enrolled1 locationACTRN12611000658910
Completed
Phase 1
A Phase I study to assess the safety of three formulations of the dermal implant ELAPR
The dermal implant ELAPR is being developed to treat the symptoms of skin aging or damage including wrinkles, scarring and photoaging.Healthy subjects are to be used in the study to assess the safety of the dermal implant.
Elastagen Pty Ltd12 enrolled1 locationACTRN12610000871044
Not Yet Recruiting
Phase 1
A comparison of intensive individualised behavioural support and traditional medical treatment for the behavioural and psychological symptoms of dementia (BPSD).
The behavioural and psychological symptoms of dementia (BPSD)
Dr Kuruvilla George, Consultant Psychiatrist and Director, Eastern Health's Aged Persons Mental Health Service90 enrolledACTRN12607000344493
Not Yet Recruiting
Phase 1
Study into the effectiveness of nitrate patches in improving urine flow and decreasing voiding problems associated with prostate enlargement
Lower urinary tract symptoms associated with benign prostatic hypertrophy
Clifford Craig Medical Research Trust75 enrolled1 locationACTRN12605000548639