Symptoms Clinical Trials

337 recruitingLast updated: June 18, 2026

There are 337 actively recruiting symptoms clinical trials across 57 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, Hong Kong, Hong Kong, Montreal, Quebec, Canada. Updated daily from ClinicalTrials.gov.


Symptoms Trials at a Glance

337 actively recruiting trials for symptoms are listed on ClinicalTrialsFinder across 6 cities in 57 countries. The largest study group is Not Applicable with 202 trials, with the heaviest enrollment activity in Boston, Hong Kong, and Montreal. Lead sponsors running symptoms studies include The University of Hong Kong, Johns Hopkins University, and Beni-Suef University.

Treatments under study

About Symptoms Clinical Trials

Looking for clinical trials for Symptoms? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Symptoms trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Symptoms clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 337 trials

Recruiting
Not Applicable

Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions

Arterial Occlusive DiseasesPainCardiovascular Diseases+12 more
Teleflex1,859 enrolled1 locationNCT07258290
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Not Applicable

Our Voices Matter: Intervention for Depression in Youth

Metabolic SyndromeDepressive SymptomsAllostatic Load
Ann & Robert H Lurie Children's Hospital of Chicago300 enrolled1 locationNCT07216326
Recruiting
Not Applicable

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

Depressive Symptoms
Children's Hospital of Philadelphia45 enrolled1 locationNCT07020572
Recruiting
Not Applicable

rTMS Combined With Aerobic Exercise for Older Adults With Mild Cognitive Impairment and Comorbid Depression

Depressive SymptomsMild Cognitive Impairment (MCI)
Cheng-Hsin General Hospital45 enrolled1 locationNCT07652775
Recruiting
Phase 3

Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications

Negative Symptoms of Schizophrenia
Minerva Neurosciences380 enrolled5 locationsNCT07565428
Recruiting
Not Applicable

ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression

DepressionAnxietyEconomic Vulnerability+1 more
University of Massachusetts, Worcester600 enrolled1 locationNCT06295250
Recruiting
Not Applicable

Water Vapor Thermal Therapy Versus Ejaculation-Sparing Bipolar Transurethral Enucleation for Benign Prostatic Hyperplasia

Benign Prostatic HyperplasiaLower Urinary Tract SymptomsEjaculatory Dysfunction
Beni-Suef University120 enrolled1 locationNCT07648888
Recruiting
Not Applicable

Michigan Men's Diabetes Project III(MenDIII): Mind and Motion

DepressionDiabetes Mellitus, Type 2Depressive Symptoms
University of Michigan80 enrolled1 locationNCT06574035
Recruiting
Not Applicable

An Ecological Momentary Intervention for the Reduction of Impairment in Somatic Symptom Disorder

Somatic Symptom Disorder (DSM-5)Persistent Physical SymptomsMedically Unexplained Symptoms+2 more
University of Vienna40 enrolled1 locationNCT07646509
Recruiting
Not Applicable

Cancer Pain Management Using a Web-based Intervention

Cancer PainCancer of BreastDepressive Symptoms
University of Texas at Austin300 enrolled1 locationNCT06085313
Recruiting
Not Applicable

Ejaculatory-Sparing HoLEP vs Standard HoLEP

Enlarged Prostate (BPH)Enlarged Prostate With Lower Urinary Tract Symptoms
Northwestern University48 enrolled1 locationNCT07631286
Recruiting
Not Applicable

Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation

AutismIntellectual DisabilityIntellectual Disabilities With Other Behavioral Symptoms
Children's Mercy Hospital Kansas City10 enrolled1 locationNCT07624448
Recruiting
Not Applicable

Mobile Intervention for Mental Health of Family Caregivers in Thailand

Depressive Symptoms, Generalized Anxiety, or Psychological Stress
Brigham and Women's Hospital400 enrolled1 locationNCT06722287
Recruiting
Not Applicable

Strength and Pain-Coping Through Resilience and Knowledge

PainDepressive SymptomsAging
Johns Hopkins University100 enrolled1 locationNCT07228520
Recruiting
Not Applicable

Ejaculation-Preserving Versus Standard Bipolar TUEP for BPH

Benign Prostatic HyperplasiaLower Urinary Tract SymptomsBenign Prostatic Obstruction
Beni-Suef University60 enrolled1 locationNCT07629479
Recruiting
Not Applicable

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

Anxiety DepressionDepressionAnxiety+3 more
University of Pittsburgh150 enrolled3 locationsNCT05658796
Recruiting
Not Applicable

ComfiJ Versus Conventional Double-J Stent for Ureteral Stent Symptoms

UrolithiasisUreteral CalculiUreteral Stent-Related Symptoms
Beni-Suef University150 enrolled3 locationsNCT07627828
Recruiting
Not Applicable

The Effects of Postbiotic Supplementation in Female Athletes

Menstrual CycleGastrointestinal Symptoms
Liverpool John Moores University100 enrolled1 locationNCT07580118
Recruiting
Not Applicable

CanSOLVE 2.0 Theme 3.1 Mind the Gap - Dialectical Behavioural Therapy (DBT) Skills Training Program Pilot

HemodialysisMental HealthHealth-related Quality of Life+2 more
University of Manitoba35 enrolled1 locationNCT07628309