Symptoms Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Symptoms clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 145 trials

Recruiting
Not Applicable

Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care

DepressionAnxietyPsychosis+1 more
Brigham and Women's Hospital45 enrolled3 locationsNCT07364825
Recruiting
Early Phase 1

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Not Applicable

Preventing Depression of Chinese American Adolescents by RRE

Subclinical Depressive Symptoms
Northeastern University110 enrolled1 locationNCT05921201
Recruiting
Not Applicable

Symptom Care at Home-Heart Failure

Heart FailureSymptoms and Signs
Emory University50 enrolled4 locationsNCT04347759
Recruiting
Phase 1

Open-Label Psilocybin Study in Transdiagnostic Population

AnxietyDepression - Major Depressive DisorderPTSD+5 more
Yale University50 enrolled1 locationNCT06442423
Recruiting
Phase 2

Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy

Prostate CancerProstate CarcinomaProstate Neoplasm+15 more
Shehzad Basaria, M.D.60 enrolled1 locationNCT06957691
Recruiting
Not Applicable

ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression

DepressionAnxietyEconomic Vulnerability+1 more
University of Massachusetts, Worcester680 enrolled1 locationNCT06295250
Recruiting
Not Applicable

The Pain Reduction Using Immersive Virtual Reality During Wound Care Evaluation Study at Maimonides (PRISM) - Pilot Study

PainNeuropsychiatric SymptomsWound Care
McGill University25 enrolled2 locationsNCT07447830
Recruiting
Not Applicable

VR-PMR for Post-Burn Symptoms

Virtual RealityAnxietyDepressive Symptoms+8 more
Johns Hopkins University34 enrolled1 locationNCT07317271
Recruiting
Not Applicable

TF-CBT for Autistic Youth Pilot Implementation - Open Pilot

AutismAutism Spectrum DisorderPTSD and Trauma-related Symptoms+2 more
Dartmouth-Hitchcock Medical Center24 enrolled1 locationNCT07420478
Recruiting
Early Phase 1

Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms

Breast CancerAromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)Joint Pain
Philip Chang30 enrolled2 locationsNCT06123286
Recruiting
Not Applicable

RCT on Running Water Sound During Urodynamic

Lower Urinary Tract Symptoms (LUTS)
Princess Margaret Hospital, Hong Kong240 enrolled2 locationsNCT07451548
Recruiting
Not Applicable

Assessing the Effects of Cool Roofs on Indoor Environments and Health

Sleep QualityDepressionDehydration+22 more
Aditi Bunker3,200 enrolled5 locationsNCT06579950
Recruiting
Phase 3

Pharmacologically Modulating the Noradrenergic Arousal System to Reduce Freezing of Gait in Parkinson's Disease: a Multi-centre and Multi-modal Approach

Parkinson's Disease (PD)Freezing of GaitFreezing of Gait Symptoms in Parkinson Disease
Radboud University Medical Center60 enrolled1 locationNCT07316296
Recruiting
Not Applicable

Accelerated Neuromodulation Therapy for Negative Symptoms of Schizophrenia

Schizophrenia and Predominant Negative Symptoms
Douglas Mental Health University Institute75 enrolled3 locationsNCT07428460
Recruiting
Not Applicable

Michigan Men's Diabetes Project III(MenDIII): Mind and Motion

DepressionDiabetes Mellitus, Type 2Depressive Symptoms
University of Michigan80 enrolled1 locationNCT06574035
Recruiting
Early Phase 1

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting
Not Applicable

BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Urinary Incontinence in Postpartum and Early Post-Childbirth Women

Urinary IncontinenceDepressive Symptoms
BTL Industries Ltd.60 enrolled3 locationsNCT07413692
Recruiting
Not Applicable

Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to Clinical Practice

Physical ActivityDepressive SymptomsInflammation+3 more
IRCCS Centro San Giovanni di Dio Fatebenefratelli120 enrolled1 locationNCT07009223
Recruiting
Not Applicable

BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women

Sexual DysfunctionUrinary IncontinenceDepressive Symptoms
BTL Industries Ltd.60 enrolled3 locationsNCT07413705