Phase 2 Symptoms Clinical Trials

22 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 22 trials

Recruiting
Phase 2

Mindfulness Engaged Neurostimulation for Depression (MEND II)

DepressionDepressive DisorderDepressive Symptoms+2 more
University of California, San Diego120 enrolled1 locationNCT07512284
Recruiting
Phase 1Phase 2

Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause

Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Phase 2

New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia

Lower Urinary Track SymptomsBPH (Benign Prostatic Hyperplasia)
Beth Israel Deaconess Medical Center242 enrolled1 locationNCT06944145
Recruiting
Phase 2

Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy

Prostate CancerProstate CarcinomaProstate Neoplasm+12 more
Shehzad Basaria, M.D.60 enrolled1 locationNCT06957691
Recruiting
Phase 1Phase 2

A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)

MELAS SyndromeLebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
George Washington University24 enrolled1 locationNCT06792500
Recruiting
Phase 2

Cannabidiol for Reduction of Brain Neuroinflammation

Depressive SymptomsBack Pain
Massachusetts General Hospital80 enrolled1 locationNCT05066308
Recruiting
Phase 2

Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS).

Vasomotor Symptoms
Tioga Pharmaceuticals120 enrolled1 locationNCT07042516
Recruiting
Phase 2Phase 3

Efficacy of Tadalafil (5mg) For Treatment of Early Storage Symptoms and Erectile Dysfunction After Endoscopic Enucleation of Prostate

Erectile DysfunctionLower Urinary Tract Symptoms
Mansoura University110 enrolled1 locationNCT05955001
Recruiting
Phase 2

Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome

Lower Urinary Tract SymptomsOveractive Bladder Syndrome
Iman Al-Naggar, PhD50 enrolled1 locationNCT06351683
Recruiting
Phase 2

Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients with BPH.

BPHLUTS(Lower Urinary Tract Symptoms)
Clinical Academic Center (2CA-Braga)70 enrolled1 locationNCT05401032
Recruiting
Phase 2Phase 3

Dog Presence and Oxytocin on Trust Towards Therapists

Depressive SymptomsHuman-Animal Interaction
Dr. Karin Hediger176 enrolled1 locationNCT06248710
Recruiting
Phase 2Phase 3

Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women

DyslipidemiasPostmenopausal SymptomsHypercholesterolemia+3 more
Dhurakij Pundit University10 enrolled1 locationNCT06220266
Recruiting
Phase 2

Beetroot Juice NO Cold Study

Respiratory Tract InfectionsCold SymptomsExhaled Nitric Oxide
Southern Methodist University150 enrolled2 locationsNCT06416228
Recruiting
Phase 1Phase 2

Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder

Autism Spectrum DisorderGastrointestinal Symptoms
The University of Texas Health Science Center, Houston70 enrolled1 locationNCT03514784
Completed
Phase 2

A pilot study of safety, tolerability and pharmacokinetics of cannabidiol therapy in symptomatic kidney failure

Chronic symptoms management in chronic kidney disease patients
University of Sydney20 enrolled1 locationACTRN12622000383763
Suspended
Phase 2

Efficacy and safety of a Chinese herbal medicine to reduce hot flushes/night sweats in women treated for breast cancer

vasomotor symptoms in breast cancer survivors
Western Sydney University84 enrolled3 locationsACTRN12617001247369
Completed
Phase 2

Evaluation of the MonaLisa Touch procedure in the treatment of postmenopausal vulvovavaginal symptoms

postmenopausal vulvovaginal symptomsVulvovaginal symptoms
GRACE Unit - School of Women's and Children's Health, UNSW Sydney, Australia78 enrolled1 locationACTRN12616001403426
Recruiting
Phase 2

A clinical study to assess the efficacy of a green-lipped mussel (GLM) extract in people with knee osteoarthritis.

Knee OsteoarthritisGastrointestinal Symptoms
Aroma New Zealand Limited110 enrolled1 locationACTRN12613000261718
Recruiting
Phase 2

Orally inhaled heparin in patients with cystic fibrosis (CF)

Pulmonary symptoms of cystic fibrosis
Vectura Limited (UK)64 enrolled4 locationsACTRN12610000328077