Syphilis Clinical Trials

4 recruiting

Frequently Asked Questions

Common questions about Syphilis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.

Syphilis InfectionSexually Transmitted Infection (STI)Treponema Pallidum+4 more
American Laboratory Products Company1,000 enrolled6 locationsNCT07089836
Recruiting

Clinical Performance Evaluation of MagIA IVD-MD Multiplex Testing (HIV/HBV/HCV/Syphilis)

HIVHBVHCV+3 more
MagIA Diagnostics2,950 enrolled2 locationsNCT07170748
Recruiting
Not Applicable

Multiplo Tp/HIV Self-Test

HIV InfectionSyphilis Infection
Unity Health Toronto900 enrolled3 locationsNCT06716450
Recruiting
Not Applicable

Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without Doxycycline

Early Syphilis, Latent, Serological Relapse After Treatment
National Taiwan University Hospital688 enrolled9 locationsNCT06069141
Recruiting
Not Applicable

The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) Study

HIVPrEP UptakeGonorrhea Female+3 more
Johns Hopkins University5,560 enrolled1 locationNCT06743204
Recruiting
Phase 3

Cefixime Clinical Trial

Human Immunodeficiency VirusSyphilis
University of Southern California400 enrolled1 locationNCT04958122
Recruiting
Not Applicable

The TRIple Elimination Model Of Mother-to-child Transmission Program (TRI-MOM)

HIVHBVSyphilis
Institut de Recherche pour le Developpement2,800 enrolled2 locationsNCT05951751
Recruiting

Vienna HIV Infection Via Sex Study

HIV InfectionsChlamydiaSyphilis+3 more
Medical University of Vienna500 enrolled1 locationNCT05326061