Thrombotic Microangiopathies Clinical Trials

8 recruitingLast updated: May 21, 2026

There are 8 actively recruiting thrombotic microangiopathies clinical trials across 9 countries. Studies span Not Applicable, Phase 2. Top locations include Paris, France, Seattle, Washington, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Thrombotic Microangiopathies Trials at a Glance

8 actively recruiting trials for thrombotic microangiopathies are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 1 trial, with the heaviest enrollment activity in Paris, Seattle, and Boston. Lead sponsors running thrombotic microangiopathies studies include Children's Hospital Medical Center, Cincinnati, Institute of Hematology & Blood Diseases Hospital, China, and Assistance Publique - Hôpitaux de Paris.

Browse thrombotic microangiopathies trials by phase

About Thrombotic Microangiopathies Clinical Trials

Looking for clinical trials for Thrombotic Microangiopathies? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Thrombotic Microangiopathies trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Thrombotic Microangiopathies clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting
Not Applicable

Efficacy and Safety of Immunosuppression, Caplacizumab and Plasma Infusion Without Therapeutic Plasma Exchange in Immune-mediated Thrombotic Thrombocytopenic Purpura

Thrombotic Microangiopathies
University Hospital, Rouen131 enrolled30 locationsNCT06291025
Recruiting

Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium

Thrombotic MicroangiopathiesHemolytic Uremic Syndrome, AtypicalHemolytic-Uremic Syndrome
Maastricht University Medical Center42 enrolled1 locationNCT04745195
Recruiting

Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center

Cardiovascular DiseasesRare DiseasesAutoimmune Diseases+5 more
Assistance Publique - Hôpitaux de Paris1,200 enrolled1 locationNCT07205861
Recruiting

Identification of Plasma Biomarkers for Early Diagnosis of Transplant-associated Thrombotic Microangiopathy

Hematopoietic Stem Cell TransplantationThrombotic Microangiopathies
Institute of Hematology & Blood Diseases Hospital, China500 enrolled1 locationNCT06102694
Recruiting

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic Stem Cell Transplant (HSCT)Thrombotic MicroangiopathiesDiffuse Alveolar Hemorrhage+2 more
Children's Hospital Medical Center, Cincinnati2,000 enrolled9 locationsNCT04098445
Recruiting
Phase 2

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

Hematopoietic Stem Cell TransplantationThrombotic Microangiopathies
Omeros Corporation18 enrolled16 locationsNCT05855083
Recruiting

Longitudinal Cohort of Thrombosis and Hemostasis Diseases

ThrombophiliaThrombosisArterial Thromboembolism+13 more
Peking University People's Hospital3,000 enrolled5 locationsNCT06727669
Recruiting

Construction of a Database for TMA

Thrombotic Microangiopathies
The First Affiliated Hospital of Soochow University500 enrolled1 locationNCT05634928