Phase 4 Tics Clinical Trials

19 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 119 of 19 trials

Recruiting
Phase 4

Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies

AntibioticsPeriodontal DiseasesPharmacokinetics
University of Geneva, Switzerland45 enrolled1 locationNCT04669717
Recruiting
Phase 4

The STOP-MED CTRCD Trial

Heart FailureCancerCardiotoxicity+2 more
Dinesh Thavendiranathan335 enrolled14 locationsNCT06183437
Recruiting
Phase 4

Investigating the Pharmacokinetics of Tafenoquine in Healthy Papua New Guinean Children

Pharmacokinetics of Tafenoquine
Curtin University30 enrolled1 locationNCT07052162
Recruiting
Phase 4

Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia

DepressionAnxietyFunctional Dyspepsia+1 more
Xijing Hospital of Digestive Diseases180 enrolled1 locationNCT07182890
Recruiting
Phase 4

Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia

DepressionAnxietyFunctional Dyspepsia+1 more
Xijing Hospital of Digestive Diseases180 enrolled1 locationNCT07187492
Recruiting
Phase 4

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4

A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer Cachexia

Clinical Characteristics and Treatment Outcomes of Malignant Tumor CachexiaMulticenter Observational Study
Changchun GeneScience Pharmaceutical Co., Ltd.495 enrolled1 locationNCT07243379
Recruiting
Phase 4

Quantifying Ocular Surface Aberrations After Tear Film Interventions

Tear Film Characteristics
University of Waterloo12 enrolled1 locationNCT06966349
Recruiting
Phase 4

Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

Pain, PostoperativePharmacokinetics
Milton S. Hershey Medical Center40 enrolled1 locationNCT03737292
Recruiting
Phase 4

Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants

Invasive AspergillosisFungal InfectionPharmacokinetics+4 more
Melbourne Health100 enrolled1 locationNCT03717623
Recruiting
Phase 4

Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot

Diabetic FootTherapeutics
Peking University Third Hospital100 enrolled1 locationNCT06062576
Recruiting
Phase 4

Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions

Pituitary AdenomaAntibiotics
St. Joseph's Hospital and Medical Center, Phoenix116 enrolled1 locationNCT03014687
Terminated
Phase 4

Cerebral blood flow changes during different entropy value targeted (entropy value 30-40 versus entropy value 50- 60 ) anesthesia induction with propofol in patients undergoing supratentorial tumor surgery.

patients with supratentorial tumor,anesthetics effect on cerebral blood flow
achmet ali40 enrolled1 locationACTRN12617000580370
Completed
Phase 4

The pharmacokinetics of intranasal droperidol in healthy volunteers.

Pharmacokinetics of intranasal drug delivery in healthy human volunteers.
Monash Health7 enrolled1 locationACTRN12614000514606
Completed
Phase 4

The effect of low dose intravenous premedication (co-induction) on cardiac output and induction of anaesthesia

Cardiac output changesAnaesthetics
Christchurch Anaesthesia Education Trust80 enrolled1 locationACTRN12610000447055
Not Yet Recruiting
Phase 4

A Case Series Investigating the efficacy of Rotation to Methadone in Palliative Patients with Cancer Related Pain

Analgesic effectiveness of rotation to methadone for palliative patients experiencing pain with both nociceptive and neuropathic qualities and that has been inadequately controlled by escalating doses of other narcotics
Brisbane South Palliative Care Collaborative20 enrolled1 locationACTRN12609001071213
Completed
Phase 4

Carbohydrate Distribution

Type 2 diabetics with HbA1c greater than 6.5mmol/L
Commonwealth Scientific Industrial Research Organisation, Human Nutrition24 enrolled1 locationACTRN12606000432516
Not Yet Recruiting
Phase 4

Pharmacokinetics of 0.25% levobupivacaine with adrenaline following caudal epidural administration in children

Pharmacokinetics in children receiving Levobupivacaine
Royal Childrens' Hospital50 enrolled1 locationACTRN12606000428561
Not Yet Recruiting
Phase 4

The effect of intrathecal pethidine on shivering in women having caesarean sections: a prospective randomised controlled trial

Shivering in women having caesarean sections under spinal anaesthetics
Box Hill Hospital, Eastern Health40 enrolled1 locationACTRN12605000065695