Phase 3 TME Clinical Trials

51 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 51 trials

Recruiting
Phase 3

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Acute Treatment of Migraine
Pfizer600 enrolled125 locationsNCT04743141
Recruiting
Phase 2Phase 3

Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery

Rectal Cancer Stage IIIRectal Cancer PatientsOrgan Preservation+2 more
Sir Mortimer B. Davis - Jewish General Hospital131 enrolled4 locationsNCT03051464
Recruiting
Phase 3

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Comparative, Phase III Study to Evaluate the Efficacy and Safety of Nuvastatic® 300mg Capsule in Reducing Cancer-Tumor in Patients With Metastatic Colorectal Cancer Receiving Standard Chemotherapy.

Colon CancerFatigue Related to Cancer Treatment
Natureceuticals Sdn Bhd250 enrolled6 locationsNCT07669454
Recruiting
Phase 3

Nuvastatic® Phase III Trial for Fatigue in Triple-Negative Breast Cancer

Breast CancerFatigue Related to Cancer Treatment
Natureceuticals Sdn Bhd250 enrolled6 locationsNCT07669467
Recruiting
Phase 3

Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia

Treatment-resistant Schizophrenia
Newron Pharmaceuticals SPA400 enrolled10 locationsNCT07184619
Recruiting
Phase 3

Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis

Acute Ischemic StrokeBrain StrokeStenting Treatment
ProMedica Health System342 enrolled1 locationNCT07356284
Recruiting
Phase 2Phase 3

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Radiotherapy Side EffectNeoadjuvant TherapyChemotherapy+8 more
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos400 enrolled1 locationNCT06758830
Recruiting
Phase 3

Ketamine Augmentation of ECT in Treatment-Resistant Depression

Major Depressive DisorderTreatment Resistant Depression
Università Vita-Salute San Raffaele30 enrolled1 locationNCT07088380
Recruiting
Phase 3

Budesonide Prophylaxis for Engraftment Syndrome After Hematopoietic Cell Transplantation

Engraftment Syndrome
Henry Ford Health System110 enrolled1 locationNCT05509933
Recruiting
Phase 3

Intra-arterial Tenecteplase for Acute Medium Vessel Occlusion Stroke

Ischemic StrokeMedium Vessel OcclusionEndovascular Treatment+1 more
Beijing Tiantan Hospital488 enrolled1 locationNCT07357987
Recruiting
Phase 3

Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma

Head & Neck CancerPostoperative Adjuvant TreatmentHead & Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University370 enrolled1 locationNCT07445048
Recruiting
Phase 3

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

Treatment Resistant DepressionRefractory Depression
University of North Carolina, Chapel Hill23 enrolled1 locationNCT06303739
Recruiting
Phase 3

Golidocitinib Versus Placebo as Maintenance Therapy for Peripheral T-Cell Lymphoma

Maintenance Treatment of Peripheral T-cell Lymphoma
Fudan University136 enrolled1 locationNCT07300514
Recruiting
Phase 2Phase 3

Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment

TreatmentSurvivalClassical Hodgkin Lymphoma+6 more
Children's Cancer Group, China96 enrolled1 locationNCT06563245
Recruiting
Phase 3

A Trial of Chinese Traditional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty

TreatmentPrecocious PubertyAcupuncture+1 more
Children's Hospital of Fudan University170 enrolled2 locationsNCT06510764
Recruiting
Phase 3

Biomarker-guided rTMS for Treatment Resistant Depression

Major Depressive DisorderTreatment Resistant Depression
Weill Medical College of Cornell University348 enrolled2 locationsNCT04041479
Recruiting
Phase 3

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Servier Bio-Innovation LLC136 enrolled114 locationsNCT06127407
Recruiting
Phase 2Phase 3

QL0911 for the Treatment of Cancer Treatment-Induced Thrombocytopenia

Cancer Treatment-induced Thrombocytopenia
Qilu Pharmaceutical Co., Ltd.235 enrolled2 locationsNCT06456528
Recruiting
Phase 3

Irinotecan Hydrochloride Liposome Injection (II)in Combination With Oxaliplatin, 5-FU/LV Versus AG for First-line Treatment of Metastatic Pancreatic Cancer

First-line Treatment of Metastatic Pancreatic Cancer
Jiangsu HengRui Medicine Co., Ltd.662 enrolled1 locationNCT07238283
Recruiting
Phase 3

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

Major Depressive DisorderTreatment Resistant Depression
Dr. Inge Winter418 enrolled12 locationsNCT05973851