Phase 1 TP53 Y220C Mutation Clinical Trials

2 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–2 of 2 trials

Recruiting

Phase 1

A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

Advanced Solid TumorsTP53 Y220C Mutation

PMV Pharmaceuticals, Inc14 enrolled5 locationsNCT07372625

Recruiting

Phase 1

A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation

Solid Tumors Harboring a TP53 Y220C Mutation

Changchun GeneScience Pharmaceutical Co., Ltd.82 enrolled1 locationNCT06908434