Phase 1 Transfusion Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1

Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO

Oxygen DeliveryCardiogenic ShockAnemia+2 more
University Hospital, Lille236 enrolled1 locationNCT05699005
Recruiting
Phase 1

RN1201 Injection in the Treatment of Antibody-Mediated Diseases

Refractory Immune-mediated Platelet Transfusion RefractorinessRelapsed or Refractory Immune Thrombocytopenia
The First Affiliated Hospital of Soochow University9 enrolled1 locationNCT07072247
Recruiting
Phase 1

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Beta-ThalassemiaSickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)+1 more
Daniel Bauer10 enrolled1 locationNCT06647979
Recruiting
Phase 1

S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion

Transfusion Related Complication
James Reynolds35 enrolled1 locationNCT03999229
Recruiting
Phase 1Phase 2

Study of CM313(SC) Injection in Subjects With Platelet Transfusion Refractoriness

Platelet Transfusion Refractoriness
Keymed Biosciences Co.Ltd110 enrolled1 locationNCT06792019
Recruiting
Phase 1Phase 2

Β-Thalassemia Treatment with KL003 Cell Injection

Transfusion Dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd.41 enrolled2 locationsNCT06280378
Recruiting
Phase 1

A Study Evaluating the Safety and Efficacy of the GMCN-508A Drug Product in Transfusion-dependent α-Thalassemia Participants

Transfusion Dependent Thalassemia
First Affiliated Hospital of Guangxi Medical University5 enrolled1 locationNCT05757245
Completed
Phase 1

Is it safe to monitor non-invasive hemoglobin in major surgery?

blood transfusionhemoglobin concentration
Ayten saracoglu20 enrolled1 locationACTRN12619001468112
Completed
Phase 1

Safety study of a test oral iron chelator in male iron-overloaded patients

Iron overload in transfusion-dependent patients
FerroKin BioSciences Inc.4 enrolled1 locationACTRN12609000213246