Phase 3 Transplant Clinical Trials
52 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 52 trials
Recruiting
Phase 3
Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients
Cytomegalovirus InfectionsKidney Transplant InfectionPancreas Transplant
University of Wisconsin, Madison90 enrolled1 locationNCT06407232
Recruiting
Phase 3
A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients
Kidney Transplant Failure and RejectionBK ViremiaKidney Transplant Infection
The University of Queensland280 enrolled13 locationsNCT05325008
Recruiting
Phase 2Phase 3
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
Kidney Transplant Rejection
Sanofi526 enrolled23 locationsNCT07412470
Recruiting
Phase 3
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction
Lung Transplant Rejection
Sanofi180 enrolled80 locationsNCT06082037
Recruiting
Phase 3
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)Solid Organ Transplant ComplicationsLymphoproliferative Disorders+2 more
Pierre Fabre Medicament115 enrolled71 locationsNCT03394365
Recruiting
Phase 2Phase 3
VABu Conditioning in Elderly AML HSCT
Acute Myeloid Leukemia (AML)Allogeneic Hematopoietic Stem Cell Transplantation Recipient
The First Affiliated Hospital of Soochow University20 enrolled1 locationNCT07583888
Recruiting
Phase 3
TACKLE-IT Trial - Treat Acute T Cell Rejection With Evidence and Confidence in Kidney Transplant Recipients
Rejection; Transplant, KidneyRejection; Transplant, Pancreas
University of Sydney540 enrolled25 locationsNCT06474273
Recruiting
Phase 3
AERIAL Trial: Antiplatelet Therapy in Heart Transplantation
Heart TransplantCardiac Allograft Vasculopathy
Ottawa Heart Institute Research Corporation135 enrolled3 locationsNCT04770012
Recruiting
Phase 3
Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation
Kidney TransplantDelayed Graft FunctionDGF
Alexion Pharmaceuticals, Inc.450 enrolled130 locationsNCT06830798
Recruiting
Phase 2Phase 3
CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients
Kidney Pancreas Transplantation
University of Wisconsin, Madison20 enrolled1 locationNCT03769298
Recruiting
Phase 3
Shingrix in Renal Transplant Recipients
Kidney FailureKidney TransplantationKidney Failure, Chronic+2 more
University of Colorado, Denver132 enrolled4 locationsNCT04128189
Recruiting
Phase 3
Kidney Transplant Preemptive Therapy or Prophylaxis for CMV Prevention in D+R Recipients
Kidney Transplant; ComplicationsKidney DiseasesCytomegalovirus (CMV)
University of California, San Francisco360 enrolled5 locationsNCT06798909
Recruiting
Phase 3
MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib
Acute Myeloid Leukemia (AML)Maintenance TherapyAllogeneic Hematopoietic Cell Transplantation (HCT)+3 more
The First Affiliated Hospital of Soochow University594 enrolled2 locationsNCT07463651
Recruiting
Phase 3
An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant
Kidney TransplantType 1 Diabetes
Vertex Pharmaceuticals Incorporated10 enrolled7 locationsNCT06832410
Recruiting
Phase 3
Fludarabine Plus Melphalan Versus Addition of Venetoclax to Fludarabine/Melphalan Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in AML/MDS Patients Aged > 50 Years: a Multicenter, Randomized, Phase 3 Trial
VenentoclaxALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATIONMyeloid Malignancies+3 more
First Affiliated Hospital of Zhejiang University186 enrolled18 locationsNCT07396480
Recruiting
Phase 3
Study Comparing Reduced Versus Standard Dose Post-transplantation Cyclophosphamide in Combination With Post-engraftment Anti-thymoglobin as Graft Versus Host Disease Prophylaxis in Alternative Donor Peripheral Stem Cell Transplantation
Allogeneic Hematopoietic Cell TransplantGraft-Versus-Host Disease
Shanghai Jiao Tong University School of Medicine316 enrolled1 locationNCT06705062
Recruiting
Phase 3
A Phase 3 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults at High Risk of Delayed Graft Function (DGF) Following Kidney Allograft Transplantation
End Stage Renal DiseaseDelayed Graft FunctionDeceased Donor Kidney Transplant
Apellis Pharmaceuticals, Inc.320 enrolled1 locationNCT07020832
Recruiting
Phase 3
Comparison of Etamsylate Versus Placebo to Prevent Bleeding in HSCT
ThrombocytopeniaHematopoietic Stem Cell Transplantation
First Affiliated Hospital of Zhejiang University404 enrolled1 locationNCT07442513
Recruiting
Phase 3
CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT
B-ALLMRD-positiveAllogenetic Hematopoietic Stem Cell Transplantation
Peking University People's Hospital70 enrolled1 locationNCT07441291
Recruiting
Phase 3
Effectiveness of an Immune-guided Cytomegalovirus Infection Preventive Strategy Compared to a Universal Prophylactic Strategy in Renal Transplant Patients
Kidney Transplant Infection
University Hospital, Rouen144 enrolled1 locationNCT05708508