Early Phase 1 Transplant Clinical Trials

13 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 113 of 13 trials

Recruiting
Early Phase 1

Concomitant Renal and Urinary Bladder Allograft Transplantation

Chronic Kidney DiseasesBladder DysfunctionNeurogenic Bladder+6 more
Mayo Clinic30 enrolled2 locationsNCT04626167
Recruiting
Early Phase 1

CAR-T Therapy Targeting CD19 and BCMA in Highly Sensitized Kidney Transplant Participants

Highly Sensitized Patients Awaiting Kidney Transplant
Tongji Hospital12 enrolled1 locationNCT07350837
Recruiting
Early Phase 1

Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT

Allogeneic Hematopoietic Stem Cell Transplantation RecipientAdenovirusCytomegalovirus+2 more
Sumithira Vasu20 enrolled2 locationsNCT03665675
Recruiting
Early Phase 1

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Skin CancerKidney Transplant Recipients
Rhode Island Hospital30 enrolled1 locationNCT05702398
Recruiting
Early Phase 1

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

Allogeneic Hematopoietic Cell Transplantation
Case Comprehensive Cancer Center20 enrolled1 locationNCT04332341
Recruiting
Early Phase 1

Prevention of Graft Rejection in Hematopoietic Stem Cell Transplant (HSCT) Recipients

Hematopoietic Stem Cell TransplantationGraft Failure
Children's Hospital Medical Center, Cincinnati20 enrolled1 locationNCT07244419
Recruiting
Early Phase 1

T Cell Therapy of Opportunistic Cytomegalovirus Infection

Hematopoietic Stem Cell TransplantCytomegalovirus InfectionsOpportunistic Infections
Mari Dallas20 enrolled1 locationNCT02982902
Recruiting
Early Phase 1

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Multiple MyelomaLymphomaHematologic Malignancy+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1

Tolerance Through Mixed Chimerism (Sip-Tego)

Kidney FailureTransplant Recipient (Kidney)Immunosuppresion+2 more
Tatsuo Kawai, MD, PhD12 enrolled1 locationNCT06972069
Recruiting
Early Phase 1

Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

Lung Transplant; Complications
Vanderbilt University Medical Center48 enrolled1 locationNCT04469842
Recruiting
Early Phase 1

Exercise as an Immune Adjuvant for Allogeneic Cell Therapies

LeukemiaHematopoetic Stem Cell TransplantationDonor Lymphocyte Infusion
University of Arizona100 enrolled1 locationNCT06643221
Completed
Early Phase 1

Adoptive Immunotherapy for Liver Cancer

Liver Transplant
Duke-Nus Medical School1 enrolled1 locationACTRN12616000129482
Not Yet Recruiting
Early Phase 1

Everolimus for the prevention of calcineurin-inhibitor-induced left ventricular hypertrophy in heart transplantation

Left ventricular hypertrophy in heart transplantation
St. Vincent`s Hospital40 enrolled4 locationsACTRN12614000387628