Phase 2 Traumatic Stress Clinical Trials
32 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 32 trials
Recruiting
Phase 2
Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD
Posttraumatic Stress DisorderPosttraumatic Headache
Northwestern University175 enrolled3 locationsNCT06608277
Recruiting
Phase 2
Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD
Alcohol Use DisorderPosttraumatic Stress Disorder
Texas A&M University200 enrolled2 locationsNCT05959434
Recruiting
Phase 2
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)
Neurocognitive FunctionPost-traumatic StressAcute Stress Disorder+1 more
University of North Carolina, Chapel Hill180 enrolled9 locationsNCT06636786
Recruiting
Phase 2
MDMA-Assisted Massed Exposure Therapy for PTSD
Post Traumatic Stress Disorder
Emory University200 enrolled1 locationNCT07288151
Recruiting
Phase 2
Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI
Traumatic Brain InjuryPost Traumatic Stress Disorder
NYU Langone Health120 enrolled1 locationNCT04550377
Recruiting
Phase 1Phase 2
Mitigating PTSD-CUD After Sexual Assault
Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841
Recruiting
Phase 2
Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms
Post Traumatic Stress DisorderPTSD
Oui Therapeutics, Inc.40 enrolled1 locationNCT07316088
Recruiting
Phase 2
Ayahuasca, Esketamine and PTSD
Posttraumatic Stress Disorder (PTSD)
University of Sao Paulo10 enrolled1 locationNCT07317206
Recruiting
Phase 2
Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.
Post Traumatic Stress Disorder
Massachusetts General Hospital96 enrolled1 locationNCT07079761
Recruiting
Phase 2Phase 3
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
DepressionPost Traumatic Stress DisorderAnxiety Disorders
University of California, San Diego128 enrolled1 locationNCT06273527
Recruiting
Phase 2
A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances
Sleep Disturbances and InsomniaPosttraumatic Stress Disorder (PTSD)
Reconnect Labs24 enrolled1 locationNCT06685965
Recruiting
Phase 2Phase 3
Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms
Post Traumatic Stress DisorderMild Traumatic Brain InjuryAutonomic Nervous System Disease+2 more
Virginia Commonwealth University148 enrolled1 locationNCT07071350
Recruiting
Phase 2
Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine
Post Traumatic Stress Disorder
Global Coalition for Adaptive Research200 enrolled10 locationsNCT05948553
Recruiting
Phase 2
Department of Defense PTSD Adaptive Platform Trial - Master Protocol
Post Traumatic Stress Disorder
Global Coalition for Adaptive Research800 enrolled10 locationsNCT05422612
Recruiting
Phase 2
Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant
Post Traumatic Stress Disorder
Global Coalition for Adaptive Research200 enrolled10 locationsNCT05948540
Recruiting
Phase 2
Suvorexant for Treatment of AUD and PTSD
InsomniaPost Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance76 enrolled2 locationsNCT06679062
Recruiting
Phase 2
Dose Optimization of MDMA-Assisted Therapy for PTSD
Posttraumatic Stress Disorder
Bronx VA Medical Center60 enrolled1 locationNCT06418178
Recruiting
Phase 2
Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans
Post Traumatic Stress DisorderOpioid-use Disorder
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance120 enrolled2 locationsNCT04360681
Recruiting
Phase 2
Enhancing Week-long Psychological Treatment for PTSD With Ketamine
Posttraumatic Stress Disorder
Yale University162 enrolled2 locationsNCT05737693
Recruiting
Phase 2
Facilitation of Extinction Retention and Reconsolidation Blockade in PTSD
Post Traumatic Stress Disorder
Boston University256 enrolled2 locationsNCT04468360