Traumatic Stress Clinical Trials

3 recruiting

Traumatic Stress Trials at a Glance

226 actively recruiting trials for traumatic stress are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 143 trials, with the heaviest enrollment activity in Houston, Boston, and New York. Lead sponsors running traumatic stress studies include VA Office of Research and Development, Karolinska Institutet, and Yale University.

Browse traumatic stress trials by phase

Treatments under study

About Traumatic Stress Clinical Trials

Looking for clinical trials for Traumatic Stress? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Traumatic Stress trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Traumatic Stress clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 226 trials

Recruiting
Not Applicable

Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel

DepressionAnxietyPosttraumatic Stress
University of Regina300 enrolled1 locationNCT04335487
Recruiting
Phase 3

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

PTSD - Post Traumatic Stress Disorder
Senseye, Inc.1,900 enrolled6 locationsNCT07280065
Recruiting
Phase 2

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

Posttraumatic Stress DisorderPosttraumatic Headache
Northwestern University175 enrolled3 locationsNCT06608277
Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+7 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting
Not Applicable

Psychotherapy Effects on Reward Processing in PTSD

Post Traumatic Stress DisorderAnhedoniaPTSD+3 more
University of Texas at Austin120 enrolled1 locationNCT06096740
Recruiting

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Healthy ControlSchizophreniaPost Traumatic Stress Disorder+4 more
Yale University100 enrolled1 locationNCT01730781
Recruiting
Early Phase 1

Mental Health in Veterans and Families After Group Therapies

Post-Traumatic Stress Disorders
Soul Medicine Institute100 enrolled1 locationNCT01327690
Recruiting
Not Applicable

Improving Cognitive Rehabilitation Outcomes

Mild Traumatic Brain InjuryPosttraumatic Stress Disorder
VA Office of Research and Development144 enrolled2 locationsNCT07055633
Recruiting
Phase 2

Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

Alcohol Use DisorderPosttraumatic Stress Disorder
Texas A&M University200 enrolled2 locationsNCT05959434
Recruiting
Not Applicable

Multicenter iTBS Neuromodulation for PTSD Treatment

Posttraumatic Stress Disorder
Second Affiliated Hospital, School of Medicine, Zhejiang University140 enrolled5 locationsNCT06434766
Recruiting
Phase 3

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

Post Traumatic Stress Disorder
Transcend Therapeutics300 enrolled19 locationsNCT07456696
Recruiting
Not Applicable

Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

Insomnia DisorderPosttraumatic Stress Disorder
VA Office of Research and Development200 enrolled1 locationNCT05780177
Recruiting
Not Applicable

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

InsomniaCardiovascular DiseasesMetabolic Disease+1 more
University of California, Los Angeles167 enrolled1 locationNCT05516277
Recruiting
Not Applicable

Multi-component Family Intervention to Lower Depression and Address Intimate Partner Violence in Nepal

DepressionPTSD - Post Traumatic Stress DisorderIntimate Partner Violence (IPV)
Possible900 enrolled1 locationNCT06834867
Recruiting
Phase 2

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

Neurocognitive FunctionPost-traumatic StressAcute Stress Disorder+1 more
University of North Carolina, Chapel Hill180 enrolled9 locationsNCT06636786
Recruiting
Phase 2

MDMA-Assisted Massed Exposure Therapy for PTSD

Post Traumatic Stress Disorder
Emory University200 enrolled1 locationNCT07288151
Recruiting
Not Applicable

Reported Experience Measurement on Reducing Patient Discomfort in Intensive Care

PTSD - Post Traumatic Stress Disorder
Almaviva Sante1,242 enrolled1 locationNCT07525284
Recruiting
Not Applicable

Trial of Acceptance and Mindfulness-based Exposure Therapy (AMBET) and Present Centered Therapy (PCT)

Cardiac Arrest (CA)PTSD - Post Traumatic Stress Disorder
Columbia University90 enrolled1 locationNCT07410481
Recruiting
Not Applicable

Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship

Alcohol Use DisorderPosttraumatic Stress DisorderCouples
Medical University of South Carolina140 enrolled1 locationNCT05786157
Recruiting
Not Applicable

Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

Post Traumatic Stress DisorderTrauma
University of Minnesota30 enrolled1 locationNCT07485231