Phase 1 Tumor, Solid Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1Phase 2
TumorGlow Intraoperative Molecular Imaging (IMI)
Tumor, Solid
University of Pennsylvania500 enrolled1 locationNCT04723810
Recruiting
Phase 1Phase 2
Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor
Lung CancerPancreas CancerThyroid Cancer+1 more
Sichuan Enray Pharmaceutical Sciences Company54 enrolled9 locationsNCT07433283
Recruiting
Phase 1
Study of RGL-270 Single Drug and Combined With Adebelimab in Patients in Patients at High Risk of Recurrence After Radical Treatment of Malignant Solid Tumors
Tumor, Solid
Xian-Jun Yu198 enrolled1 locationNCT07348042
Recruiting
Phase 1
T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor
Tumor, Solid
Ting Deng9 enrolled1 locationNCT06484790
Recruiting
Phase 1
T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor
Tumor, Solid
TingBo Liang9 enrolled1 locationNCT06478251
Recruiting
Phase 1
Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment
Advanced Solid TumorTumorTumor, Solid
Aadi Bioscience, Inc.28 enrolled2 locationsNCT05661461
Recruiting
Phase 1
Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
Pancreatic CancerMelanomaTumor, Solid
UNC Lineberger Comprehensive Cancer Center45 enrolled1 locationNCT03454035
Recruiting
Phase 1
A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab
Advanced Solid TumorCancerMetastatic Cancer+2 more
Nectin Therapeutics Ltd90 enrolled6 locationsNCT05378425
Recruiting
Phase 1Phase 2
LEU01101: Safety and Preliminary Efficacy of LEU011 in Solid Tumours.
Tumor, Solid
Leucid Bio17 enrolled2 locationsNCT06193902
Recruiting
Phase 1
T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor
Tumor, Solid
Tao Zhang9 enrolled2 locationsNCT06484556
Recruiting
Phase 1Phase 2
A Study of PARG Inhibitor XNW29016 in Patients With Advanced Solid Tumors Who Failed Standard Treatment
Tumor, Solid
Evopoint Biosciences Inc.132 enrolled1 locationNCT06987500
Recruiting
Phase 1Phase 2
AD1208 in Subjects With Any Progressive, Locally Advanced or Metastatic Solid Tumors
Solid TumorSolid Tumor, AdultSolid Tumor Cancer+4 more
Avelos Therapeutics Inc.36 enrolled3 locationsNCT06911333
Recruiting
Phase 1Phase 2
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
Advanced Solid TumorCancerNon-small Cell Lung Cancer+4 more
OncoResponse, Inc.168 enrolled4 locationsNCT06090266