Phase 1 Tumor, Solid Clinical Trials

13 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 113 of 13 trials

Recruiting
Phase 1Phase 2

TumorGlow Intraoperative Molecular Imaging (IMI)

Tumor, Solid
University of Pennsylvania500 enrolled1 locationNCT04723810
Recruiting
Phase 1Phase 2

Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor

Lung CancerPancreas CancerThyroid Cancer+1 more
Sichuan Enray Pharmaceutical Sciences Company54 enrolled9 locationsNCT07433283
Recruiting
Phase 1

Study of RGL-270 Single Drug and Combined With Adebelimab in Patients in Patients at High Risk of Recurrence After Radical Treatment of Malignant Solid Tumors

Tumor, Solid
Xian-Jun Yu198 enrolled1 locationNCT07348042
Recruiting
Phase 1

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Tumor, Solid
Ting Deng9 enrolled1 locationNCT06484790
Recruiting
Phase 1

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Tumor, Solid
TingBo Liang9 enrolled1 locationNCT06478251
Recruiting
Phase 1

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Advanced Solid TumorTumorTumor, Solid
Aadi Bioscience, Inc.28 enrolled2 locationsNCT05661461
Recruiting
Phase 1

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

Pancreatic CancerMelanomaTumor, Solid
UNC Lineberger Comprehensive Cancer Center45 enrolled1 locationNCT03454035
Recruiting
Phase 1

A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab

Advanced Solid TumorCancerMetastatic Cancer+2 more
Nectin Therapeutics Ltd90 enrolled6 locationsNCT05378425
Recruiting
Phase 1Phase 2

LEU01101: Safety and Preliminary Efficacy of LEU011 in Solid Tumours.

Tumor, Solid
Leucid Bio17 enrolled2 locationsNCT06193902
Recruiting
Phase 1

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Tumor, Solid
Tao Zhang9 enrolled2 locationsNCT06484556
Recruiting
Phase 1Phase 2

A Study of PARG Inhibitor XNW29016 in Patients With Advanced Solid Tumors Who Failed Standard Treatment

Tumor, Solid
Evopoint Biosciences Inc.132 enrolled1 locationNCT06987500
Recruiting
Phase 1Phase 2

AD1208 in Subjects With Any Progressive, Locally Advanced or Metastatic Solid Tumors

Solid TumorSolid Tumor, AdultSolid Tumor Cancer+4 more
Avelos Therapeutics Inc.36 enrolled3 locationsNCT06911333
Recruiting
Phase 1Phase 2

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

Advanced Solid TumorCancerNon-small Cell Lung Cancer+4 more
OncoResponse, Inc.168 enrolled4 locationsNCT06090266