Early Phase 1 Tumor Clinical Trials
73 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 73 trials
Recruiting
Early Phase 1
NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors
Advanced Solid Tumors
Base Therapeutics (Shanghai) Co., Ltd.18 enrolled1 locationNCT07561437
Recruiting
Early Phase 1
Pencil Beam Scanning in Patients With Renal Tumors
Wilms TumorRenal Tumor
Children's Hospital of Philadelphia28 enrolled1 locationNCT03810651
Recruiting
Early Phase 1
Study of Letrozole in Recurrent Gliomas
Brain Tumor
University of Cincinnati39 enrolled1 locationNCT03122197
Recruiting
Early Phase 1
Exploring the Clinical Value of RT01-89Zr PET Imaging in Solid Tumors
Solid Tumors
Nanolattix Biotechnology Co., Ltd.10 enrolled1 locationNCT07505069
Recruiting
Early Phase 1
Clinical Study on the Efficacy and Safety of CAR-DC in the Treatment of Advanced Solid Tumors
Advanced Solid Tumors
Peking University Shenzhen Hospital10 enrolled1 locationNCT07504445
Recruiting
Early Phase 1
Functionally Enhanced ALPP-Targeted Engineered T Cells in Advanced Solid Tumors
Solid Tumor
TCRCure Biopharma Ltd.24 enrolled1 locationNCT07487597
Recruiting
Early Phase 1
A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX37 in Advanced/Metastatic Solid Tumors
NSCLCAdvanced/Metastatic Solid Tumors
Shanghai Henlius Biotech254 enrolled2 locationsNCT07274813
Recruiting
Early Phase 1
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
CNS Embryonal TumorCNS, Medulloblastoma
C17 Council15 enrolled12 locationsNCT06942039
Recruiting
Early Phase 1
Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors
Solid Tumor
St. Jude Children's Research Hospital25 enrolled3 locationsNCT05645523
Recruiting
Early Phase 1
A Single-Arm, Open-Label Clinical Study GK01 Cell Injection in Subjects With Advanced Solid Tumors.
Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD10 enrolled1 locationNCT07414316
Recruiting
Early Phase 1
HEAT Trial (HER2 Antibody Therapy With Lutetium-177)
Advanced Solid TumorsHER2 Gene Mutation
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06824155
Recruiting
Early Phase 1
B-GLUCANCER2 : A Pilot Study Evaluating a New Method for Cancer Detection by Measuring the Activity of Different Glycosidase Enzymes in the Plasma of Patients With a Localized Cancer.
Breast CancerPancreatic CancerPulmonary Cancer+4 more
Poitiers University Hospital220 enrolled1 locationNCT07236177
Recruiting
Early Phase 1
A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]
Primary Malignant Peripheral Nerve Sheath Tumors
University of Minnesota8 enrolled1 locationNCT06693284
Recruiting
Early Phase 1
This is a Multi-Center Study of IBI3026 in Participants With Locally Advanced, Unresectable or Metastatic Solid Tumors
Solid Tumor
Innovent Biologics Technology Limited (Shanghai R&D Center)300 enrolled1 locationNCT07327632
Recruiting
Early Phase 1
A Clinical Study of GK02 in Malignant Ascites
Malignant Ascites Caused by Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD9 enrolled1 locationNCT07378436
Recruiting
Early Phase 1
Safety and Efficacy of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors
Advanced Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences36 enrolled1 locationNCT07349160
Recruiting
Early Phase 1
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Breast CancerBladder CarcinomaEsophageal Carcinoma+11 more
Var2 Pharmaceuticals32 enrolled1 locationNCT06645808
Recruiting
Early Phase 1
A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)
Gastrointestinal Tumor
Shanghai Juncell Therapeutics50 enrolled1 locationNCT04960072
Recruiting
Early Phase 1
A Study of GC203 TIL in PDCA (RJ)
Pancreatic CancerTreatment Side EffectsTumor Infiltrating Lymphocytes+1 more
Shanghai Juncell Therapeutics10 enrolled1 locationNCT06828328
Recruiting
Early Phase 1
A Clinical Study on Evaluating Intravenous Administration of IDOV-SAFE
Advanced Malignant Solid Tumor of Digestive System
Peking University89 enrolled1 locationNCT06380309