Phase 1 UF Clinical Trials
23 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 23 trials
Recruiting
Phase 1
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment
Liver DiseasesHepatic Insufficiency
Incyte Corporation16 enrolled4 locationsNCT07559474
Recruiting
Phase 1
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.
Hepatic Insufficiency
Eli Lilly and Company36 enrolled3 locationsNCT07401862
Recruiting
Phase 1Phase 2
Effects of Allogenic Umbilical Cord-Derived Mesenchymal Stem Cells on Patients With Rotator Cuff Disease
Rotator Cuff Disease
Seoul National University Hospital21 enrolled1 locationNCT06794294
Recruiting
Phase 1
A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems
Hepatic Insufficiency
Boehringer Ingelheim44 enrolled3 locationsNCT06957756
Recruiting
Phase 1Phase 2
CBD for Pain Following Orthopedic Shoulder Surgery
Shoulder Osteoarthritisrotator cuff injuries
The Methodist Hospital Research Institute80 enrolled1 locationNCT06381791
Recruiting
Phase 1
First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiency
Luteal Phase InsuffiencyProgesterone Delivery
Calla Lily Clinical Care Ltd20 enrolled1 locationNCT07136922
Recruiting
Phase 1
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
Cystic Fibrosis-related DiabetesPancreatic Insufficiency
University of Pennsylvania15 enrolled2 locationsNCT06995651
Recruiting
Phase 1
A Trial of Hydroxynidone Capsules in Single-dose Administration for Patients With Renal Insufficiency
Renal Insufficiency, Chronic
Beijing Continent Pharmaceutical Co, Ltd.56 enrolled1 locationNCT07262333
Recruiting
Phase 1
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
Kidney DiseaseRenal ImpairmentRenal Insufficiency, Chronic+3 more
Eli Lilly and Company28 enrolled2 locationsNCT07426380
Recruiting
Phase 1
A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function
Renal Insufficiency
Eli Lilly and Company32 enrolled4 locationsNCT07137689
Recruiting
Phase 1Phase 2
JAG201 Gene Therapy Study in Children & Adults With SHANK3 Haploinsufficiency
Phelan-McDermid SyndromeSHANK3 Haploinsufficiency
Jaguar Gene Therapy, LLC6 enrolled3 locationsNCT06662188
Recruiting
Phase 1
Home-based Vision Therapy
convergence insufficiency
VA Office of Research and Development45 enrolled1 locationNCT06886737
Recruiting
Phase 1Phase 2
Tuberoplasty Versus Balloon Spacer
Rotator Cuff Tears
University of Minnesota40 enrolled1 locationNCT06735170
Recruiting
Phase 1Phase 2
Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults
ObesityInsufficient Sleep
University of Minnesota90 enrolled1 locationNCT06226077
Recruiting
Phase 1
A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment
HealthyHepatic Insufficiency
Eli Lilly and Company32 enrolled3 locationsNCT07165002
Recruiting
Phase 1Phase 2
Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency
Premature Ovarian Insufficiency
Yan Hongli50 enrolled1 locationNCT07115082
Recruiting
Phase 1
A Pharmacokinetics and Safety Study of Azvudine Tablets in Subjects With Mild-To-Moderate GFR Decline in Renal Insufficiency and in Healthy Subjects
Renal Insufficiency
Henan Genuine Biotech Co., Ltd.40 enrolled1 locationNCT07001436
Recruiting
Phase 1Phase 2
Probiotic Supplementation and Disease Progression in CKD: A Randomized Trial
Kidney Disease, ChronicRenal Insufficiency, ChronicGut Dysbiosis+1 more
Mansoura University72 enrolled1 locationNCT06863194
Recruiting
Phase 1
A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function
Hepatic Insufficiency
X4 Pharmaceuticals48 enrolled4 locationsNCT06858696
Completed
Phase 1
Clinical evaluation of a novel suture anchor for rotator cuff repairs – ATOK Anchor
Patients over the age of 60, with a less than 3cm rotator cuff tear involving the supraspinatus and at least part of the infraspinatus tendons. Patients will have failed non-operative management.
Assoc Prof Michael Sandow20 enrolled3 locationsACTRN12617000800325