Phase 1 Ulcer Clinical Trials
34 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 34 trials
Recruiting
Phase 1
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 1Phase 2
A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis
Moderate to Severe Ulcerative Colitis
Genentech, Inc.24 enrolled1 locationNCT06693908
Recruiting
Phase 1
Phase 1 Study of VELGRAFT, a Living Cellular Construct, in the Management of Chronic Diabetic Foot Ulcers Which Have Attained Granulation Tissue
Diabetic Foot Ulcer (DFU)Granulation of Chronic Diabetic Wounds
Ayu, Inc.24 enrolled1 locationNCT07498218
Recruiting
Phase 1Phase 2
A Study of MB-001 in Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)
Mage Biologics100 enrolled1 locationNCT07374471
Recruiting
Phase 1Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Ulcerative Colitis (UC)
Xencor, Inc.270 enrolled52 locationsNCT06619990
Not Yet Recruiting
Phase 1
A randomised controlled trial to evaluate the drug TL-003 in healthy adults aged 18-55.
Ulcerative Colitis
SAPRO Consulting Pty Ltd.64 enrolled1 locationACTRN12626000354381
Recruiting
Phase 1Phase 2
FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach
Ulcerative ColitisClostridium Difficile
Fondazione Policlinico Universitario Agostino Gemelli IRCCS64 enrolled1 locationNCT06071312
Recruiting
Phase 1Phase 2
Superdonor FMT in Patients With Ulcerative Colitis
Active Ulcerative Colitis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS42 enrolled1 locationNCT05739864
Recruiting
Phase 1Phase 2
Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers
Diabetic Foot UlcerWagner Grade 1 - 2
Eluciderm Inc15 enrolled4 locationsNCT07396376
Recruiting
Phase 1
Compare and Evaluate the Safety and PK Data of a Single Dose Administration of 'AD-115A' or 'AD-1151'
Gastric Ulcer
Addpharma Inc.46 enrolled1 locationNCT07385235
Recruiting
Phase 1
R-3750 in Patients With Mild to Moderate Ulcerative Colitis
Ulcerative ColitisUlcerative Colitis ChronicUlcerative Colitis Chronic Mild+1 more
Rise Therapeutics LLC36 enrolled4 locationsNCT05666960
Recruiting
Phase 1
Evaluate the Safety, Tolerability, PK and PD of SAD of Intravenously Adminsterted ALTB-268 in Healthy Participants
Ulcerative Colitis (UC)
AltruBio Inc.24 enrolled1 locationNCT07350577
Recruiting
Phase 1Phase 2
Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic Sclerosis
Systemic SclerosisDigital Ulcer
UMC Utrecht20 enrolled1 locationNCT03211793
Recruiting
Phase 1Phase 2
A Study of AC-101 Tablets in Participants With Moderate to Severe Active Ulcerative Colitis
Ulcerative Colitis
Accro Bioscience (Suzhou) Limited24 enrolled1 locationNCT07083193
Recruiting
Phase 1Phase 2
Safety and Preliminary Efficacy of TrophiPatch, an Adipose-Derived Stromal Cell Patch for Chronic Leg Ulcers
Diabetic Foot Ulcer (DFU)Venous Leg Ulcer (VLU)
Nicolò Brembilla18 enrolled1 locationNCT07048054
Recruiting
Phase 1Phase 2
Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy
Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
Children's Hospital Medical Center, Cincinnati116 enrolled3 locationsNCT03847467
Recruiting
Phase 1Phase 2
A Study of XSTEM-VLU in Patients With Difficult-to-heal Venous Leg Ulcers
Venous Leg Ulcer
Xintela AB6 enrolled4 locationsNCT05549609
Recruiting
Phase 1
NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers
Diabetic Foot Ulcer
NOxy Health Products, LLC40 enrolled2 locationsNCT06402565
Recruiting
Phase 1Phase 2
Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease
Ulcerative Colitis (UC)Crohn Disease (CD)
University Medical Center Groningen18 enrolled1 locationNCT06606808
Recruiting
Phase 1
A Study of NP-201 Acetate Injection in Healthy Adult Volunteers and in Patients With Mild-To-Moderate Active Ulcerative Colitis
Active Ulcerative ColitisActive Ulcerative Colitis (UC)Healthy Adult Volunteers
NIBEC Co., Ltd.24 enrolled1 locationNCT06681389