Ulcer Clinical Trials

501 recruitingLast updated: June 18, 2026

There are 501 actively recruiting ulcer clinical trials across 71 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include New York, New York, United States, Miami, Florida, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Ulcer Trials at a Glance

501 actively recruiting trials for ulcer are listed on ClinicalTrialsFinder across 6 cities in 71 countries. The largest study group is Not Applicable with 192 trials, with the heaviest enrollment activity in New York, Miami, and Houston. Lead sponsors running ulcer studies include Takeda, AbbVie, and Eli Lilly and Company.

Treatments under study

About Ulcer Clinical Trials

Looking for clinical trials for Ulcer? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Ulcer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Ulcer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 501 trials

Recruiting
Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 4

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

Crohn's DiseaseUlcerative Colitis
Takeda400 enrolled101 locationsNCT06581328
Recruiting
Phase 2

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Ulcerative Colitis
Eli Lilly and Company252 enrolled149 locationsNCT07186101
Recruiting
Not Applicable

Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers

Diabetic Foot Ulcer
NuScience Medical Biologics, LLC132 enrolled8 locationsNCT06938685
Recruiting
Not Applicable

Intestinal Organoids

Crohn DiseaseDigestive System DiseasesInflammatory Bowel Disease, Ulcerative Colitis Type
Rennes University Hospital90 enrolled1 locationNCT05294107
Recruiting

Immune Regulation in Ulcerative Colitis or Crohn s Disease

Ulcerative ColitisInflammatory Bowel DiseaseChrohn's Disease
National Institute of Allergy and Infectious Diseases (NIAID)1,000 enrolled1 locationNCT00001184
Recruiting
Not Applicable

Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers

Diabetic Foot Ulcer
Omeza, LLC130 enrolled10 locationsNCT07161830
Recruiting

A Study of Ozanimod in Pregnant Women With Ulcerative Colitis and Their Offspring

Ulcerative Colitis
Bristol-Myers Squibb1,182 enrolled1 locationNCT05953402
Recruiting
Not Applicable

BOOM-IBD2 Pivotal Clinical Trial

Inflammatory Bowel DiseasesUlcerative Colitis
Boomerang Medical137 enrolled19 locationsNCT06571669
Recruiting
Phase 3

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's DiseaseUlcerative Colitis
Takeda70 enrolled1 locationNCT06405087
Recruiting
Phase 2

Confirmatory Clinical Study in Active Ulcerative Colitis

Colitis Ulcerative
MRM Health NV204 enrolled10 locationsNCT07296315
Recruiting
Phase 3

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis
Sanofi671 enrolled40 locationsNCT07185009
Recruiting
Phase 2

Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis

Digital Ulcers in Systemic Sclerosis
Topadur Pharma AG15 enrolled6 locationsNCT06954597
Recruiting
Phase 2

A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

Ulcerative ColitisColitis Ulcerative
Merck Sharp & Dohme LLC100 enrolled9 locationsNCT07463183
Recruiting
Phase 4

Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis(UPFRONT)

Acute Severe Ulcerative Colitis
Yongquan Shi46 enrolled4 locationsNCT07546097
Recruiting

Individualizing Anti-TNF Therapy in Patients With Inflammatory Bowel Disease

IBD (Inflammatory Bowel Disease)Ulcerative Colitis (UC)Crohn Disease (CD)
Shmuel Kivity, MD40 enrolled1 locationNCT07644117
Recruiting
Phase 2Phase 3

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Colitis Ulcerative
Bristol-Myers Squibb120 enrolled90 locationsNCT05076175
Recruiting
Phase 1Phase 2

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

Ulcerative Colitis (UC)
Xencor, Inc.270 enrolled66 locationsNCT06619990
Recruiting
Phase 1

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

Ulcerative ColitisUlcerative Colitis ChronicUlcerative Colitis Chronic Mild+1 more
Rise Therapeutics LLC36 enrolled5 locationsNCT05666960
Recruiting
Phase 3

A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis

Ulcerative Colitis
Alfasigma S.p.A.80 enrolled47 locationsNCT06865417