Phase 1 Urinary Clinical Trials
27 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 27 trials
Recruiting
Phase 1
FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3
Urinary Bladder NeoplasmsNeoplasm MetastasisUreteral Neoplasms
Eli Lilly and Company535 enrolled84 locationsNCT05614739
Recruiting
Phase 1
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Triple-Negative Breast CancerEsophageal CancerPancreatic Cancer+11 more
Eli Lilly and Company420 enrolled31 locationsNCT06465069
Recruiting
Phase 1
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer1,006 enrolled159 locationsNCT04389632
Recruiting
Phase 1
Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies
Urothelial CancerBladder CancerGenitourinary Cancer+2 more
National Cancer Institute (NCI)100 enrolled1 locationNCT04235777
Recruiting
Phase 1Phase 2
A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)
Urinary Bladder NeoplasmsBladder Cancer
Merck Sharp & Dohme LLC45 enrolled14 locationsNCT07222488
Recruiting
Phase 1Phase 2
Muscle Fiber Fragment Treatment for Urinary Incontinence
Urinary Incontinence
Wake Forest University10 enrolled1 locationNCT01953263
Recruiting
Phase 1Phase 2
A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age
Urinary Tract Infections
GlaxoSmithKline448 enrolled8 locationsNCT06702449
Recruiting
Phase 1Phase 2
A Study of BL-M07D1 in Patients With a Variety of Solid Tumors Including Locally Advanced or Metastatic HER2-positive/Low-expressing Urinary and Gastrointestinal Tumors
Her2-positive/Low-expression Urinary and Digestive Tract Tumors
Sichuan Baili Pharmaceutical Co., Ltd.42 enrolled1 locationNCT06031584
Recruiting
Phase 1
Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
Breast CancerOvarian CancerCervical Cancer+6 more
M.D. Anderson Cancer Center40 enrolled1 locationNCT04038619
Recruiting
Phase 1
Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
Malignant Solid NeoplasmClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+41 more
M.D. Anderson Cancer Center800 enrolled1 locationNCT03819296
Recruiting
Phase 1
Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
Breast CancerColorectal, CancerOvarian Cancer+4 more
National Cancer Institute (NCI)210 enrolled1 locationNCT06253520
Recruiting
Phase 1
A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors
Advanced Solid TumorMetastatic Solid TumorRecurrent Solid Tumor+1 more
Eli Lilly and Company490 enrolled28 locationsNCT06238479
Recruiting
Phase 1
Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
Lower Urinary Tract Obstructive SyndromeRenal Failure CongenitalCongenital Renal Anomaly Nos+1 more
Mayo Clinic40 enrolled1 locationNCT03723564
Recruiting
Phase 1
Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting
Phase 1Phase 2
Post-operative Urinary Retention (POUR) Following Thoracic Surgery
Urinary Retention
Hackensack Meridian Health127 enrolled1 locationNCT03609580
Recruiting
Phase 1
Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers
Bacterial InfectionsRespiratory Tract InfectionsUrinary Tract Infections+1 more
Joincare Pharmaceutical Group Industry Co., Ltd66 enrolled1 locationNCT07207291
Recruiting
Phase 1Phase 2
Phage Therapy for Recurrent UTIs in Kidney Transplant Recipients
Urinary Tract Infection, Recurrent
University of California, San Diego32 enrolled1 locationNCT06409819
Recruiting
Phase 1Phase 2
HTL0039732 in Participants With Advanced Solid Tumours
SarcomaUrinary Bladder NeoplasmsUterine Cervical Neoplasms+11 more
Cancer Research UK150 enrolled5 locationsNCT05944237
Recruiting
Phase 1
Allogeneic Use of Expanded Mesenchymal Stem Cells Derived From Adipose Tissue (HC106), Female Urinary Incontinence Women Over 50 Years Old
Urinary Incontinence, Stress
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz60 enrolled6 locationsNCT06738576
Recruiting
Phase 1
An Open Label, Adaptive Design Evaluation, Crossover Study of the Safety, Pharmacokinetics and Pharmacodynamics of Various RECCE®327 Intravenous Dose and Infusion Rates
Life threatening infectious diseaseUrinary Tract Infection
Recce Pharmaceuticals Ltd16 enrolled2 locationsACTRN12623000448640