Phase 3 Urinary Clinical Trials

30 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 30 trials

Recruiting
Phase 3

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer ( EV-309 )

Urinary Bladder NeoplasmsUrothelial Cancer
Astellas Pharma Global Development, Inc.390 enrolled1 locationNCT07566156
Recruiting
Phase 3

Pivotal Study of Voro Urologic Scaffold

Radical ProstatectomyStress Urinary Incontinence (SUI)
Levee Medical, Inc.266 enrolled19 locationsNCT06873581
Recruiting
Phase 3

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

Urothelial CarcinomaUpper Urinary Tract Urothelial Carcinoma
UroGen Pharma Ltd.70 enrolled52 locationsNCT06774131
Recruiting
Phase 2Phase 3

Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms

Urinary IncontinenceOveractive BladderUrologic Diseases+1 more
Northwestern University66 enrolled1 locationNCT05878951
Recruiting
Phase 3

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Urinary Bladder NeoplasmsImmune Checkpoint InhibitorsMethotrexate+4 more
AstraZeneca150 enrolled59 locationsNCT06960577
Recruiting
Phase 3

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Urinary Incontinence, Stress
Eli Lilly and Company1,000 enrolled136 locationsNCT07202884
Recruiting
Phase 3

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Urinary Bladder NeoplasmsNeoplasm MetastasisCarcinoma, Transitional Cell
Eli Lilly and Company450 enrolled281 locationsNCT07218380
Recruiting
Phase 3

Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine

Nerve BlockAnesthesia, SpinalArthroplasties, Knee Replacement+1 more
University of Toronto50 enrolled1 locationNCT07050277
Recruiting
Phase 3

Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)

Urinary Incontinence in Children
University of Aarhus236 enrolled5 locationsNCT06551246
Recruiting
Phase 2Phase 3

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations

Ovarian NeoplasmsColorectal NeoplasmsUrinary Bladder Neoplasm+8 more
Cancer Research UK30 enrolled27 locationsNCT05786716
Recruiting
Phase 3

Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women

Recurrent Urinary Tract Infections in Women
TCM Biotech International Corp.348 enrolled13 locationsNCT07184827
Recruiting
Phase 3

Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in Carbapenem-Resistant Enterobacteriaceae Infections

Hospital-acquired Bacterial Pneumonia (HABP)Ventilator-associated Bacterial Pneumonia (VABP)Complicated Intra-abdominal Infection (cIAI)+2 more
Qilu Pharmaceutical Co., Ltd.80 enrolled1 locationNCT07089186
Recruiting
Phase 2Phase 3

Efficacy of Tadalafil (5mg) For Treatment of Early Storage Symptoms and Erectile Dysfunction After Endoscopic Enucleation of Prostate

Erectile DysfunctionLower Urinary Tract Symptoms
Mansoura University110 enrolled1 locationNCT05955001
Recruiting
Phase 3

Function of Tamsulosin in Older Males Undergoing Surgery with Indwelling Catheter

Postoperative Urinary Tract Infection
Emory University212 enrolled3 locationsNCT06257576
Recruiting
Phase 3

Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery

Postoperative Urinary Retention (POUR)
TriHealth Inc.166 enrolled1 locationNCT06843538
Recruiting
Phase 3

A Trial of HRS-8427 in the Treatment of Adults With Complicated Urinary Tract Infection, Including Acute Pyelonephritis

Complicated Urinary Tract Infection(cUTI), Including Acute Pyelonephritis(AP)
Jiangsu HengRui Medicine Co., Ltd.578 enrolled1 locationNCT06569056
Recruiting
Phase 3

Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary Cancers

Prostate CarcinomaGenito Urinary CancerErectile Function
Regina Elena Cancer Institute158 enrolled2 locationsNCT06717711
Recruiting
Phase 3

Medications for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

Enlarged Prostate With Lower Urinary Tract Symptoms
Tanta University150 enrolled1 locationNCT06491108
Recruiting
Phase 3

Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections

Urinary Tract Infections
University of Sydney300 enrolled5 locationsNCT05709028
Recruiting
Phase 3

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder NeoplasmsTreatment OutcomeImmunotherapy, Active+3 more
Fujian Medical University Union Hospital76 enrolled1 locationNCT06441110