Vaginal Atrophy Clinical Trials

15 recruitingLast updated: May 21, 2026

There are 15 actively recruiting vaginal atrophy clinical trials across 8 countries. Studies span Not Applicable, Phase 4, Phase 2, Phase 3. Top locations include Laguna Hills, California, United States, Brooklyn, New York, United States, Brussels, Brussels Capital, Belgium. Updated daily from ClinicalTrials.gov.


Vaginal Atrophy Trials at a Glance

15 actively recruiting trials for vaginal atrophy are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Laguna Hills, Brooklyn, and Brussels. Lead sponsors running vaginal atrophy studies include Stratpharma AG, Azure Biotech Inc., and Arkopharma Australia.

Browse vaginal atrophy trials by phase

About Vaginal Atrophy Clinical Trials

Looking for clinical trials for Vaginal Atrophy? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Vaginal Atrophy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Vaginal Atrophy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Phase 2

Proof of Concept Study of Vaginal AZU-101 in Vulvovaginal Atrophy in Postmenopausal Women

Vulvo Vaginal Atrophy (VVA)
Azure Biotech Inc.90 enrolled1 locationNCT06197568
Recruiting
Phase 3

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage 0 Breast Cancer AJCC v8+9 more
Alliance for Clinical Trials in Oncology250 enrolled2 locationsNCT05379153
Recruiting

Determining the Extent of the Genitourinary Syndrome of Menopause Burden in Breast Cancer Survivors

Breast CancerGenitourinary Syndrome of Menopause (GSM)Vulvovaginal Atrophy+1 more
Jessa Hospital264 enrolled1 locationNCT07563621
Recruiting
Not Applicable

Efficacy and Safety of Vaginal Radiofrequency for Vulvovaginal Atrophy in Breast Cancer Patients

Breast CancerVaginal DrynessVulvovaginal Atrophy
Centre Oscar Lambret75 enrolled1 locationNCT06900374
Recruiting
Phase 4

Postpartum Vaginal Estrogen for Breastfeeding Patients

BreastfeedingVaginal AtrophyPostpartum Sexual Dysfunction
University Hospitals Cleveland Medical Center100 enrolled1 locationNCT05457972
Recruiting
Not Applicable

VALOR: Vaginal Atrophy & Long-term Observation of Recovery

Atrophic vaginitisGenitourinary Syndrome of MenopauseVaginal Atrophy+3 more
Stratpharma AG2,000 enrolled14 locationsNCT05953090
Recruiting
Phase 4

ASSIST-VLA: Assessment of Symptom-Specific Improvement in Diagnosed Vaginal Atrophy Following Laser Therapy

Atrophic vaginitisGenitourinary Syndrome of Menopause (GSM)Vaginal Atrophy
Stratpharma AG10 enrolled1 locationNCT07346287
Recruiting
Phase 4

Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo

Vaginal AtrophyPostmenopausal Disorderrecurrent urinary tract infection
Maimonides Medical Center100 enrolled1 locationNCT04807894
Recruiting
Phase 4

GRACE-trial: a Randomized Active-controlled Trial for vulvovaGinal atRophy in breAst Cancer Patients on Endocrine Therapy.

Breast CancerVulvovaginal Atrophy
University Hospital, Ghent160 enrolled1 locationNCT05562518
Recruiting
Not Applicable

Clinical and Molecular Study to Evaluate the Effect of the Pixel CO2 Laser (FemiLiftTM) for the Treatment of Vulvo-Vaginal Atrophy

Vaginal AtrophyVulvar Atrophy
Hillel Yaffe Medical Center20 enrolled1 locationNCT07024667
Recruiting
Not Applicable

Treatment of Vulvo-vaginal Atrophy (VVA) Using Vaginal Dilator in Addition to Usual Treatment

Vulvo Vaginal AtrophyGenitourinary Syndrome of Menopause (GSM)Vaginal Atrophy in Breast Cancer Patients+4 more
Centre Hospitalier Universitaire Saint Pierre160 enrolled1 locationNCT06828640
Recruiting
Not Applicable

Pelvic Health Rehabilitation After Breast and Gynecologic Cancer

Breast Cancer FemaleGynecologic CancersIncontinence+4 more
Laval University20 enrolled2 locationsNCT06822582
Recruiting
Not Applicable

Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser

Postmenopausal PeriodVaginal AtrophyVaginal prolapse
MeLSyTech, Ltd120 enrolled1 locationNCT05335317
Recruiting
Not Applicable

Efficacy of Fractional CO2 Laser Treatment in Post-Menopausal Women With Vaginal Atrophy

Post Menopausal Vaginal Atrophy
Cairo University20 enrolled1 locationNCT06726746
Recruiting
Phase 2

Phyto-Soya Vaginal Gel Study

Menopausal Vaginal Atrophy
Arkopharma Australia60 enrolled1 locationACTRN12606000020583