Venous Leg Ulcer Clinical Trials

31 recruiting

Frequently Asked Questions

Common questions about Venous Leg Ulcer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 34 trials

Recruiting
Phase 3

A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)

Venous Leg Ulcer (VLU)
MediWound Ltd216 enrolled25 locationsNCT06568627
Recruiting
Not Applicable

Suprasorb®X+PHMB Pro vs Suprasorb®X+PHMB in Treatment of Infected Venous Leg Ulcers

Venous Leg Ulcer
Lohmann & Rauscher150 enrolled9 locationsNCT07211243
Recruiting
Not Applicable

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Venous Leg Ulcers

Venous Leg Ulcer
NuScience Medical Biologics, LLC10 enrolled2 locationsNCT07061613
Recruiting
Not Applicable

Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC

Diabetic Foot UlcerVenous Leg Ulcer
Surgenex180 enrolled2 locationsNCT06515093
Recruiting
Phase 3

Tissue Repair Gel in Venous Leg Ulcers (US)

WoundsWound HealVenous Ulcer+4 more
TR Therapeutics312 enrolled33 locationsNCT06707090
Recruiting
Phase 4

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

Venous UlcerDiabetic Foot UlcerUlcer+6 more
BioLab Holdings50 enrolled1 locationNCT07364630
Recruiting
Not Applicable

Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC

Venous InsufficiencyVenous Leg UlcerNon-infected Venous Leg Ulcer+2 more
BioStem Technologies60 enrolled23 locationsNCT06811909
Recruiting
Not Applicable

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

Diabetic Foot Ulcers (DFUs)Venous Leg Ulcers (VLUs)
Reprise Biomedical, Inc.20 enrolled2 locationsNCT06939673
Recruiting
Phase 4

A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL

Diabetic Foot Ulcer (DFU)Venous Leg Ulcer (VLU)
HealthTech Wound Care150 enrolled10 locationsNCT07172893
Recruiting
Not Applicable

PMCF Study of Debridement Pad

Venous Leg UlcerDiabetic UlcersArterial Leg Ulcer
Advanced Medical Solutions Ltd.184 enrolled1 locationNCT07255937
Recruiting
Not Applicable

The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study

Venous UlcerVenous StenosisVenous Occlusion+7 more
W.L.Gore & Associates165 enrolled27 locationsNCT05489588
Recruiting
Phase 4

Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg Ulcers

Venous Leg Ulcer (VLU)
AOTI Ltd.212 enrolled1 locationNCT06754735
Recruiting
Not Applicable

CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

Diabetic Foot Ulcer (DFU)Venous Leg UlcerWound; Foot
Capsicure, LLC165 enrolled7 locationsNCT07046767
Recruiting

Reducing Skin Tone Inequities in Chronic Venous Insufficiency

Venous Leg Ulcer (VLU)Chronic Venous Insufficiency, CVIChronic Venous Insufficiency C2 or Higher+1 more
King's College London51 enrolled2 locationsNCT06798766
Recruiting
Not Applicable

Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy

Venous Leg Ulcer
Wake Forest University Health Sciences20 enrolled1 locationNCT03716167
Recruiting
Not Applicable

INNOVEN: Efficacy of Porcine Placental Extracellular Matrix Plus Standard of Care (SOC) Versus SOC Alone

Wound HealVenous Leg Ulcer
ConvaTec Inc.120 enrolled1 locationNCT06606210
Recruiting
Phase 4

Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers

Diabetic Foot UlcerDiabetic FootFoot Ulcer, Diabetic+6 more
BioLab Holdings650 enrolled1 locationNCT07089602
Recruiting
Not Applicable

Human Amniotic Membrane On Venous Leg Ulcers In an Elderly Population

Venous Leg Ulcer
BioLab Holdings150 enrolled9 locationsNCT06544564
Recruiting
Phase 1Phase 2

Safety and Preliminary Efficacy of TrophiPatch, an Adipose-Derived Stromal Cell Patch for Chronic Leg Ulcers

Diabetic Foot Ulcer (DFU)Venous Leg Ulcer (VLU)
Nicolò Brembilla18 enrolled1 locationNCT07048054
Recruiting
Phase 1Phase 2

A Study of XSTEM-VLU in Patients With Difficult-to-heal Venous Leg Ulcers

Venous Leg Ulcer
Xintela AB6 enrolled4 locationsNCT05549609