ClinicalTrialsFinder

Phase 2 X-Linked Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 1–13 of 13 trials

Recruiting
Phase 2

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Immune DysregulationPrimary Immune Regulatory DisorderChronic Granulomatous Disease+12 more
Paul Szabolcs25 enrolled1 locationNCT07284641
Recruiting
Phase 1Phase 2

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

X-linked Severe Combined Immunodeficiency (XSCID)
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled1 locationNCT01306019
Recruiting
Phase 1Phase 2

Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease

X-Linked Chronic Granulomatous Disease
Ensoma15 enrolled9 locationsNCT06876363
Recruiting
Phase 1Phase 2

Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators

X-linked Myotubular Myopathy
Astellas Gene Therapies9 enrolled4 locationsNCT07052929
Recruiting
Phase 1Phase 2

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Chronic Granulomatous Disease (CGD)X-Linked Chronic Granulomatous Disease
National Institute of Allergy and Infectious Diseases (NIAID)10 enrolled1 locationNCT06325709
Recruiting
Phase 2

A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis Pigmentosa

X-Linked Retinitis Pigmentosa (XLRP)
Beacon Therapeutics10 enrolled6 locationsNCT07174726
Recruiting
Phase 1Phase 2

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Gene TherapySevere Combined Immunodeficiency, X-Linked
David Williams12 enrolled4 locationsNCT03311503
Recruiting
Phase 1Phase 2

A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia

X-linked Hypophosphatemia
Kyowa Kirin Co., Ltd.24 enrolled9 locationsNCT06525636
Recruiting
Phase 2

Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD

Chronic Granulomatous Disease X-linked (X-CGD)
IRCCS San Raffaele3 enrolled2 locationsNCT03055247
Recruiting
Phase 1Phase 2

SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection

SCID, X-Linked
Shenzhen Geno-Immune Medical Institute10 enrolled2 locationsNCT03217617
Recruiting
Phase 2

Intraamniotic Administrations of ER004 to Male Subjects With X-linked Hypohidrotic Ectodermal Dysplasia

X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED)
EspeRare Foundation20 enrolled8 locationsNCT04980638
Recruiting
Phase 1Phase 2

Gene Therapy for RPGR Gene Mutation-associated X-linked Retinitis Pigmentosa

X-Linked Retinitis Pigmentosa (XLRP)
Frontera Therapeutics32 enrolled1 locationNCT06492850
Not Yet Recruiting
Phase 2

Acetazolamide in X-linked Retinoschisis

X-linked Retinoschisis
The University of Sydney30 enrolled1 locationACTRN12610000476033